[HTML][HTML] The limitless future of RNA therapeutics

TR Damase, R Sukhovershin, C Boada… - … in bioengineering and …, 2021 - frontiersin.org
Recent advances in the generation, purification and cellular delivery of RNA have enabled
development of RNA-based therapeutics for a broad array of applications. RNA therapeutics …

[HTML][HTML] Sustainable technologies for liposome preparation

L Maja, K Željko, P Mateja - The Journal of Supercritical Fluids, 2020 - Elsevier
Liposome possesses a great number of advantages and therefore they can be used for a
variety of applications. Among other things, they can serve as useful drug carriers in …

Nanoparticle-based drug delivery systems for induction of tolerance and treatment of autoimmune diseases

H Li, YG Yang, T Sun - Frontiers in bioengineering and biotechnology, 2022 - frontiersin.org
Autoimmune disease is a chronic inflammatory disease caused by disorders of immune
regulation. Antigen-specific immunotherapy has the potential to inhibit the autoreactivity of …

Design and development of 5-fluorouracil loaded biodegradable magnetic microspheres as site-specific drug delivery vehicle for cancer therapy

S Ayyanaar, R Bhaskar, S Esthar, M Vadivel… - Journal of Magnetism …, 2022 - Elsevier
The major limitation of present cancer chemotherapeutic agents is the poor selectivity of anti-
cancer drug and the resultant toxicity. To circumvent this limitation intense research is …

Optimization of novel naproxen-loaded chitosan/carrageenan nanocarrier-based gel for topical delivery: Ex vivo, histopathological, and in vivo evaluation

S Noreen, F Pervaiz, A Ashames, M Buabeid… - Pharmaceuticals, 2021 - mdpi.com
Naproxen (NAP) is commonly used for pain, inflammation, and stiffness associated with
arthritis. However, systemic administration is linked with several gastrointestinal tract (GIT) …

Improved controlled release and brain penetration of the small molecule S14 using PLGA nanoparticles

V Nozal, E Rojas-Prats, I Maestro, C Gil… - International Journal of …, 2021 - mdpi.com
Phosphodiesterase 7 (PDE7) is an enzyme responsible for the degradation of cyclic
adenosine monophosphate (cAMP), an important cellular messenger. PDE7's role in …

Nanoparticle platforms for antigen-specific immune tolerance

EB Thorp, C Boada, C Jarbath, X Luo - Frontiers in immunology, 2020 - frontiersin.org
Innovative approaches in nanoparticle design have facilitated the creation of new
formulations of nanoparticles that are capable of selectively calibrating the immune …

E2-Loaded Microcapsules and Bone Marrow–Derived Mesenchymal Stem Cells with Injectable Scaffolds for Endometrial Regeneration Application

Y Wu, S Gu, JM Cobb, GH Dunn, TA Muth… - … Engineering Part A, 2024 - liebertpub.com
Bone marrow–derived mesenchymal stem cells (BMSCs) have been recognized as new
candidates for the treatment of serious endometrial injuries. However, owing to the local …

A novel combination for the treatment of small cell lung cancer: Active targeted irinotecan and stattic co-loaded PLGA nanoparticles

FB Arslan, K Öztürk, E Tavukçuoğlu, SC Öztürk… - International Journal of …, 2023 - Elsevier
Polymeric nanoparticles are widely used drug delivery systems for cancer treatment due to
their properties such as ease of passing through biological membranes, opportunity to …

3D printed scaffold based on type I collagen/PLGA_TGF-β1 nanoparticles mimicking the growth factor footprint of human bone tissue

F Banche-Niclot, C Licini, G Montalbano, S Fiorilli… - Polymers, 2022 - mdpi.com
In bone regenerative strategies, the controlled release of growth factors is one of the main
aspects for successful tissue regeneration. Recent trends in the drug delivery field increased …