X-ray free electron lasers (XFELs) have the potential to revolutionize macromolecular
structural biology due to the unique combination of spatial coherence, extreme peak …

Ultrafast radiographic imaging and tracking (U-RadIT) use state-of-the-art ionizing particle
and light sources to experimentally study sub-nanosecond transients or dynamic processes …

Angiotensin II type 1 receptor (AT 1 R) is a G protein-coupled receptor that serves as a
primary regulator for blood pressure maintenance. Although several anti-hypertensive drugs …

Abstract Melatonin (N-acetyl-5-methoxytryptamine) is a neurohormone that maintains
circadian rhythms by synchronization to environmental cues and is involved in diverse …

In liquid phase chemistry dynamic solute–solvent interactions often govern the path, ultimate
outcome, and efficiency of chemical reactions. These steps involve many-body movements …

Eiger is a single-photon counting x-ray pixel detector being developed at the Paul Scherrer
Institut (PSI) for applications at synchrotron light sources. It follows the widely utilized and …

G protein–coupled receptors (GPCRs) represent a large superfamily of membrane proteins
that mediate cell signaling and regulate a variety of physiological processes in the human …

Introduction: X-ray crystallography has made important contributions to modern drug
development but its application to many important drug targets has been extremely …

Understanding how ice nucleates and grows into larger crystals is of crucial importance for
many research fields. The purpose of this study was to shed light on the phase and structure …

The ability to study chemical dynamics on ultrafast timescales has greatly advanced with the
introduction of X-ray free electron lasers (XFELs) providing short pulses of intense X-rays …