From quiescence to activation and myogenic differentiation, muscle stem cells (MuSCs)
experience drastic alterations in their signaling activity and metabolism. Through balanced …

Mitochondria are double membrane-bound organelles the network morphology of which in
cells is shaped by opposing events of fusion and fission executed by dynamin-like GTPases …

Propionic acid (PPA) is used to study the role of mitochondrial dysfunction in
neurodevelopmental conditions like autism spectrum disorders. PPA is known to disrupt …

Mitochondria are highly dynamic organelles which undergo constant fusion and fission as
part of the mitochondrial quality control. In genetic diseases and age-related …

Lactate leads to the imbalance of mitochondria homeostasis, which then promotes vascular
calcification. PARP1 can upregulate osteogenic genes and accelerate vascular calcification …

Peroxisomes are highly dynamic, oxidative organelles with key metabolic functions in
cellular lipid metabolism, such as the β-oxidation of fatty acids and the synthesis of myelin …

The dynamic regulation of mitochondria through fission and fusion is essential for
maintaining cellular homeostasis. In this study, we discovered a role of coactivator …

The cytoplasm of eukaryotes is dynamically zoned by membrane-bound and membraneless
organelles. Cytoplasmic zoning allows various biochemical reactions to take place at the …

Mitochondria-endoplasmic reticulum contacts (MERCs), also called endoplasmic reticulum
(ER)-mitochondria contact sites (ERMCS), are the membrane domains, where these two …

Mitochondria-endoplasmic reticulum contacts (MERCs), also called endoplasmic reticulum
(ER)-mitochondria contact sites (ERMCS), are the membrane domains, where these two …