Fibrin plays an essential role in hemostasis as both the primary product of the coagulation
cascade and the ultimate substrate for fibrinolysis. Fibrinolysis efficiency is greatly …

Annexins are Ca2+ and phospholipid binding proteins forming an evolutionary conserved
multigene family with members of the family being expressed throughout animal and plant …

S100 is a multigenic family of non-ubiquitous Ca2+-modulated proteins of the EF-hand type
expressed in vertebrates exclusively and implicated in intracellular and extracellular …

Annexin A2 is a pleiotropic calcium-and anionic phospholipid-binding protein that exists as
a monomer and as a heterotetrameric complex with the plasminogen receptor protein …

Simple Summary In this review, we present a detailed discussion of how the plasminogen-
activation system is utilized by tumor cells in their unrelenting attack on the tissues …

A multigenic family of Ca2+-binding proteins of the EF-hand type known as S100 comprises
19 members that are differentially expressed in a large number of cell types. Members of this …

Annexin A2 is a calcium-dependent, phospholipid-binding protein found on various cell
types. It is up-regulated in various tumor types and plays multiple roles in regulating cellular …

Human papillomaviruses (HPVs) infect epithelia and can lead to the development of lesions,
some of which have malignant potential. HPV type 16 (HPV16) is the most oncogenic …

The aggregation and membrane fusion properties of annexin II are modulated by the
association with a regulatory light chain called p11. p11 is a member of the S100 EF-hand …

The identification of circulating tumor antigens or their related autoantibodies provides a
means for early cancer diagnosis as well as leads for therapy. The purpose of this study was …