Modern immunosuppression regimens effectively control acute rejection and decrease graft
loss in the first year after transplantation; however, these regimens do not have a durable …

Solid organ transplantation is a curative therapy for hundreds of thousands of patients with
end-stage organ failure. However, long-term outcomes have not improved, and nearly half of …

The 9th Banff Conference on Allograft Pathology was held in La Coruna, Spain on June 23–
29, 2007. A total of 235 pathologists, clinicians and scientists met to address unsolved …

Early subclinical inflammation in kidney transplants is associated with later graft fibrosis and
dysfunction. Regulatory T cells (Tregs) can reverse established inflammation in animal …

Kidney allograft rejection can occur in clinically stable patients, but long-term significance is
unknown. We determined whether early recognition of subclinical rejection has long-term …

Background. Late graft failure (LGF) is believed to be the consequence of immunologic and
nonimmunologic insults leading to progressive deterioration in kidney function. We studied …

Context Kidney graft function after transplantation can be improved through pharmacological
donor pretreatment to limit organ injury from cold preservation. Objective To determine …

Background Development of noninvasive molecular assays to improve disease diagnosis
and patient monitoring is a critical need. In renal transplantation, acute rejection (AR) …

Discrepancy analysis comparing two diagnostic platforms offers potential insights into both
without assuming either is always correct. Having optimized the Molecular Microscope …

Inflammation within areas of interstitial fibrosis and tubular atrophy (i-IFTA) is associated with
adverse outcomes in kidney transplantation. We evaluated i-IFTA in 429 indication-and …