Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
Recent advances in exosome-mediated nucleic acid delivery for cancer therapy
Y Zhang, Q Liu, X Zhang, H Huang, S Tang… - Journal of …, 2022 - Springer
Cancer is a leading public health problem worldwide. Its treatment remains a daunting
challenge, although significant progress has been made in existing treatments in recent …
challenge, although significant progress has been made in existing treatments in recent …
Molecular biomarkers in cancer
VK Sarhadi, G Armengol - Biomolecules, 2022 - mdpi.com
Molecular cancer biomarkers are any measurable molecular indicator of risk of cancer,
occurrence of cancer, or patient outcome. They may include germline or somatic genetic …
occurrence of cancer, or patient outcome. They may include germline or somatic genetic …
Autophagy and cancer drug resistance in dialogue: pre-clinical and clinical evidence
Y Qin, M Ashrafizadeh, V Mongiardini, B Grimaldi… - Cancer letters, 2023 - Elsevier
The emergence of drug resistance is a major challenge for oncologists. Resistance can be
categorized as acquired or intrinsic; the alteration of several biological mechanisms …
categorized as acquired or intrinsic; the alteration of several biological mechanisms …
Extracellular vesicles and particles impact the systemic landscape of cancer
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
Liquid biopsy: Exosomal microRNAs as novel diagnostic and prognostic biomarkers in cancer
Background Detecting cancer at an early stage before clinical manifestation could be an
effective strategy to decrease cancer mortality. Thus, identifying liquid biopsy biomarkers …
effective strategy to decrease cancer mortality. Thus, identifying liquid biopsy biomarkers …
Beclin1-mediated interplay between autophagy and apoptosis: New understanding
K Prerna, VK Dubey - International journal of biological macromolecules, 2022 - Elsevier
The definition for autophagy holds a 'single'meaning as a conserved cellular process that
constitutes a recycling pathway for damaged organelles and long-lived proteins to maintain …
constitutes a recycling pathway for damaged organelles and long-lived proteins to maintain …
Mesenchymal stem cell-derived exosomes loaded with miR-155 inhibitor ameliorate diabetic wound healing
P Gondaliya, AA Sayyed, P Bhat, M Mali… - Molecular …, 2022 - ACS Publications
Diabetic wounds are one of the debilitating complications that affect up to 20% of diabetic
patients. Despite the advent of extensive therapies, the recovery rate is unsatisfactory, and …
patients. Despite the advent of extensive therapies, the recovery rate is unsatisfactory, and …
[HTML][HTML] Exosomes, autophagy and ER stress pathways in human diseases: Cross-regulation and therapeutic approaches
Exosomal release pathway and autophagy together maintain homeostasis and survival of
cells under stressful conditions. Autophagy is a catabolic process through which cell entities …
cells under stressful conditions. Autophagy is a catabolic process through which cell entities …
MiR-155 inhibitor-laden exosomes reverse resistance to cisplatin in a 3D tumor spheroid and xenograft model of oral cancer
AA Sayyed, P Gondaliya, M Mali, A Pawar… - Molecular …, 2021 - ACS Publications
Cisplatin resistance is one of the major concerns in the treatment of oral squamous cell
carcinoma (OSCC). Accumulating evidence suggests microRNA (miRNA) dysregulation as …
carcinoma (OSCC). Accumulating evidence suggests microRNA (miRNA) dysregulation as …