Atropisomerism is a stereochemical behavior portrayed by three-dimensional molecules that
bear rotationally restricted σ bond. Akin to the well-represented point-chiral molecules …

Enantiomers, where chirality arises from restricted rotation around a single bond, are
atropisomers. Due to the unique nature of the origins of their chirality, synthetic strategies to …

This tutorial review provides a systematic overview of the available methodologies for the
atroposelective transformation of (heterobiaryl) biaryl precursors toward the synthesis of …

Continued development of the Sonogashira coupling has made it a well established and
versatile reaction for the straightforward formation of C–C bonds, forging the carbon …

Catalytic dynamic kinetic asymmetric transformation (DyKAT) provides a powerful tool to
access chiral stereoisomers from racemic substrates. Such transformation has been widely …

Conjugate addition is among the most important synthetic protocols for constructing carbon
skeletons and is widely used to synthesize natural products and drugs. However …

Atroposelective synthesis of axially chiral biaryls by palladium‐catalyzed C− H olefination,
using tert‐leucine as an inexpensive, catalytic, and transient chiral auxiliary, has been …

The 3 d metals have been identified as economic and sustainable alternatives to palladium,
the frequently used metal in transition-metal-catalysed cross-couplings. However, cobalt has …

An atroposelective Ir‐catalyzed dynamic kinetic resolution (DKR) of 2‐(quinolin‐8‐yl)
benzaldehydes/1‐naphthaldehydes by transfer hydrogenative coupling of allyl acetate is …

Transition-metal-catalyzed C–H bond functionalization has known a rapid evolution in the
last years, offering modern strategies for reaching high molecular complexity in a step-and …