Most of the anti-inflammatory drugs in clinical practice are becoming outdated owing to their
potential side and adverse effects. These are found to be highly unsafe for long term use …

Two new series of pyrrolizine-5-carboxamides were synthesized and evaluated for their
anticancer and anti-inflammatory activities. The new compounds exhibited potent cytotoxicity …

Described herein is the Rh (III)‐catalyzed [3+ 2] annulations and C2‐alkenylations of indoles
with 1, 3‐diynes, which deliver the synthetically important 3H‐pyrrolo [1, 2‐a] indol‐3‐ones …

A straightforward synthesis of indolizines and pyrrolo [1, 2-a] pyrazines was performed
through a cascade condensation/cyclization/aromatization reaction of substituted 2-formyl-N …

Herein, we have presented a weak acid-promoted tandem aza-Michael–aldol strategy for
the synthesis of diversely fused pyrrolo [1, 2-a] quinoline (tricyclic to pentacyclic scaffolds) by …

Due to the emergence of multidrug-resistant strains of yeasts belonging to the Candida
genus, there is an urgent need to discover antifungal agents directed at alternative …

In this work two synthetic approaches to introduce nitrile moieties into bio‐based derived
furanic compounds were investigated, ie, dehydration of aldoximes and Knoevenagel …

We describe a synthetic approach for pyrrolizine-3-one derivatives and their photophysical
properties. These compounds are prepared by a series of reactions employing the …

吡咯里嗪类化合物是一种重要的双环融合的杂环化合物, 其核心骨架中含有桥头氮,
通常存在于具有生物活性的化合物中, 在植物, 昆虫, 动物, 海洋生物和微生物的次级代谢产物中 …

In order to discover novel anti-inflammatory agents, a series of compounds obtained by
appending chalcone moieties on dehydroepiandrosterone were designed and synthesized …