A review of biomedical multiphoton microscopy and its laser sources

C Lefort - Journal of physics D: Applied physics, 2017 - iopscience.iop.org
Multiphoton microscopy (MPM) has been the subject of major development efforts for about
25 years for imaging biological specimens at micron scale and presented as an elegant …

[HTML][HTML] Methodological advances in imaging intravital axonal transport

JN Sleigh, A Vagnoni, AE Twelvetrees… - F1000Research, 2017 - ncbi.nlm.nih.gov
Axonal transport is the active process whereby neurons transport cargoes such as
organelles and proteins anterogradely from the cell body to the axon terminal and …

Freeform gradient-index media: a new frontier in freeform optics

DH Lippman, NS Kochan, T Yang, GR Schmidt… - Optics …, 2021 - opg.optica.org
Freeform optics enable irregular system geometries and high optical performance by
leveraging rotational variance. To this point, for both imaging and illumination, freeform …

Feasibility studies of multimodal nonlinear endoscopy using multicore fiber bundles for remote scanning from tissue sections to bulk organs

H Bae, M Rodewald, T Meyer-Zedler, TW Bocklitz… - Scientific Reports, 2023 - nature.com
Here, we report on the development and application of a compact multi-core fiber optical
probe for multimodal non-linear imaging, combining the label-free modalities of Coherent …

Multimodal optical analysis of meningioma and comparison with histopathology

M Zanello, F Poulon, P Varlet, F Chretien… - Journal of …, 2017 - Wiley Online Library
Meningioma is the most frequent primary central nervous system tumor. The risk of
recurrence and the prognosis are correlated with the extent of the resection that ideally …

Two‐photon optical imaging, spectral and fluorescence lifetime analysis to discriminate urothelial carcinoma grades

B Pradere, F Poulon, E Comperat… - Journal of …, 2018 - Wiley Online Library
In the framework of urologic oncology, mini‐invasive procedures have increased in the last
few decades particularly for urothelial carcinoma. One of the essential elements in the …

Characterization of fiber ultrashort pulse delivery for nonlinear endomicroscopy

A Ibrahim, F Poulon, R Habert, C Lefort, A Kudlinski… - Optics …, 2016 - opg.optica.org
In this work, we present a detailed characterization of a small-core double-clad photonic
crystal fiber, dedicated and approved for in vivo nonlinear imaging endomicroscopy. A …

Observation of SARS-CoV-2 viral particles using electron microscopy-guided multiphoton microscopy

C Lefort, E Ferrandon, M Courant… - … Optical Imaging IV, 2024 - spiedigitallibrary.org
We tested the ability of multiphoton microscopy (MPM) devices to produce label-free images
of the virus Sars-Cov-2 responsible for the Covid global health crisis of the years 2020-2022 …

Nanosecond coherent anti-Stokes Raman scattering for particle size characterization

F El Bassri, C Lefort, E Capitaine… - Optical Biopsy XIV …, 2016 - spiedigitallibrary.org
Particle size analyzers based on laser scattering commonly make use of light diffraction and
scattering around the particle considered in its medium. For particle size below 50 μm …

A multimodal two-photon fluorescence endomicroscope and its associated tissue database to discriminate brain tumors intraoperatively

H Mehidine - 2020 - theses.hal.science
Standard of care in brain tumors management primarily consists of achieving a maximal safe
resection, by removing all cancerous zones while preserving healthy eloquent adjacent …