Rett Syndrome (RTT) is a rare and severe X-linked developmental brain disorder that occurs
primarily in females, with a ratio of 1: 10.000. De novo mutations in the Methyl-CpG Binding …

Glial cells are key players in the proper formation and maintenance of the nervous system,
thus contributing to neuronal health and disease in humans. However, little is known about …

Sleep has numerous advantages for aligning clinical and preclinical (basic neuroscience)
studies of neuropsychiatric illness. Sleep has high translational relevance, because the …

Rett Syndrome (RTT, OMIM 312750), a unique rare neurodevelopmental disorder, mostly
affects females and causes severe multi-disabilities including poor sleep. This meta-analysis …

Due to the discovery of Rett Syndrome (RTT) genetic mutations, animal models have been
developed. Sleep research in RTT animal models may unravel novel neural mechanisms for …

Abstract Objective/background Methyl-CpG-binding protein 2 (MeCP2) is of utmost
importance in neuronal function. We aim to characterize phenotypic traits in the sleep of …

Sleep disorders in humans are increasingly appreciated to be not only widespread but also
detrimental to multiple facets of physical and mental health. Recent work has begun to shed …

Proteins containing a methyl‐CpG‐binding domain (MBD) bind 5mC and convert the
methylation pattern information into appropriate functional cellular states. The correct …

Reproductive isolation and speciation are driven by the convergence of environmental and
genetic variation. The integration of these variation sources is thought to occur through …

Rett syndrome (RTT) is a progressive neurodevelopmental disease, which affects almost
exclusively the female gender (prevalence of about 1: 10,000). RTT symptoms are usually …