Orally ingestible medical devices offer significant opportunity in the diagnosis and treatment
of gastrointestinal conditions. Their development necessitates the use of models that …

The majority of newly discovered oral drugs are poorly water soluble, and co-administration
with lipids has proven effective in significantly enhancing bioavailability of some compounds …

This study aimed to develop a biopredictive dissolution method for desvenlafaxine ER
tablets using design of experiments (DoE) and physiologically based biopharmaceutics …

Abstract Knowledge about the region-specific absorption profiles from the gastrointestinal
tract of orally administered drugs is a critical factor guiding dosage form selection in drug …

A thorough study of mild and environmentally friendly electrochemical-induced
hydroxylation of aryl halides without a catalyst is presented. The best protocol consists of …

Background Venlafaxine (VEN) is a commonly utilized medication for alleviating depression
and anxiety disorders. The presence of genetic polymorphisms gives rise to considerable …

Purpose: Desvenlafaxine succinate (DSV) is a water soluble anti-depressant drug, which is
rapidly absorbed after oral administration exaggerating its side effects. The current work …

Abstract Background and Objective Peramivir is a novel antiviral agent approved for the
treatment of severe influenza. However, the development of oral formulation of peramivir has …

The in vivo performances of most drugs after extravascular administration are fitted well with
the two-compartment pharmacokinetic (PK) model, but the estimation of absorption rate …

The objective of this study was to develop a dissolution test in order to establish an in vitro–
in vivo correlation (IVIVC) model for desvenlafaxine succinate monohydrate (DVSM) …