Computational modeling of methylation impact of AML drivers reveals new pathways and refines AML risk-stratification

B Gurun, JW Tyner, E Demir, BJ Druker, PT Spellman - bioRxiv, 2023 - biorxiv.org
Decades before its clinical onset, epigenetic changes start to accumulate in the progenitor
cells of Acute Myelogenous Leukemia (AML). Delineating these changes can improve risk …