Loss of normal kidney function affects more than 10% of the population and contributes to
morbidity and mortality. Kidney diseases are currently treated with immunosuppressive …

Chronic kidney disease (CKD) is a major public health issue, due to its effect on the quality
of life of patients and by the huge costs incurred in treating this disease. It is an irreversible …

The global burden of chronic kidney disease is rising. The etiologies, heterogeneous, and
arterial hypertension, are key factors contributing to the development and progression of …

Current research on hypertension utilizes more than fifty animal models that rely mainly on
stable increases in systolic blood pressure. In experimental hypertension, grading or scoring …

Background Biopsy-based studies on nephrosclerosis are lacking and the
clinicopathological predictors for progression of chronic kidney disease (CKD) are not well …

Objectives This study aimed to investigate the clinicopathological characteristics and
prognosis of normotensive and hypertensive IgAN patients with ischemic renal injury …

Introduction Hypertensive nephrosclerosis is considered the second most common cause of
end-stage renal disease (ESRD), but it is still an insufficiently studied and controversial …

Purpose To identify the clinical characteristics, histopathological features, and prognosis of
kidney disease in a large cohort of elderly patients from Northeast China. Methods We …

Background Nephrosclerosis is an increasingly reason for dialysis in Japan. However,
kidney biopsy specimens for hypertensive nephrosclerosis are very limited; thus, the …

Background Elabela, a recently discovered hormonal peptide containing 32 amino acids, is
a ligand for the apelin receptor. It can lower blood pressure and attenuate renal fibrosis …