Dyspneic and non-dyspneic (silent) hypoxemia in COVID-19: possible neurological mechanism

M Nouri-Vaskeh, A Sharifi, N Khalili, R Zand… - Clinical neurology and …, 2020 - Elsevier
SARS-CoV-2 mainly invades respiratory epithelial cells by adhesion to angiotensin-
converting enzyme 2 (ACE-2) and thus, infected patients may develop mild to severe …

Nature and human well-being: The olfactory pathway

GN Bratman, C Bembibre, GC Daily, RL Doty… - Science …, 2024 - science.org
The world is undergoing massive atmospheric and ecological change, driving
unprecedented challenges to human well-being. Olfaction is a key sensory system through …

[HTML][HTML] Emissions from modern engines induce distinct effects in human olfactory mucosa cells, depending on fuel and aftertreatment

L Mussalo, S Avesani, MA Shahbaz, T Závodná… - Science of the Total …, 2023 - Elsevier
Ultrafine particles (UFP) with a diameter of≤ 0.1 μm, are contributors to ambient air pollution
and derived mainly from traffic emissions, yet their health effects remain poorly …

[HTML][HTML] NAM-based prediction of point-of-contact toxicity in the lung: A case example with 1, 3-dichloropropene

M Moreau, J Fisher, ME Andersen, A Barnwell… - Toxicology, 2022 - Elsevier
Time, cost, ethical, and regulatory considerations surrounding in vivo testing methods render
them insufficient to meet existing and future chemical safety testing demands. There is a …

[HTML][HTML] An alzheimer's disease patient-derived olfactory stem cell model identifies gene expression changes associated with cognition

LM Rantanen, M Bitar, R Lampinen, R Stewart, H Quek… - Cells, 2022 - mdpi.com
An early symptom of Alzheimer's disease (AD) is an impaired sense of smell, for which the
molecular basis remains elusive. Here, we generated human olfactory neurosphere-derived …

A mechanistic view on the neurotoxic effects of air pollution on central nervous system: risk for autism and neurodegenerative diseases

S Shabani - Environmental Science and Pollution Research, 2021 - Springer
Many reports have shown a strong association between exposure to neurotoxic air
pollutants like heavy metal and particulate matter (PM) as an active participant and …

[HTML][HTML] Variation in the concentration and regional distribution of magnetic nanoparticles in human brains, with and without Alzheimer's disease, from the UK

J Hammond, BA Maher, IAM Ahmed, D Allsop - Scientific Reports, 2021 - nature.com
The presence of magnetic nanoparticles (MNPs) in the human brain was attributed until
recently to endogenous formation; associated with a putative navigational sense, or with …

Long-term particulate matter 2.5 exposure and dementia: a systematic review and meta-analysis

S Cheng, Y Jin, Y Dou, Y Zhao, Y Duan, H Pei, P Lyu - Public Health, 2022 - Elsevier
Objectives This study aimed to analyse the existing evidence on the association between
particulate matter 2.5 (PM 2.5) and dementia, including two of its subtypes, namely …

Progress in Mechanisms, Pathways and Cohort Studies About the Effects of PM2.5 Exposure on the Central Nervous System

M Ye, J Yang, J Li, Y Wang, W Chen, L Zhu… - Reviews of …, 2023 - Springer
An increasing number of studies have shown that particulate matter (PM) exposure can
produce damaging effects on respiratory and cardiovascular systems, however, whether PM …

[HTML][HTML] Traffic-related ultrafine particles impair mitochondrial functions in human olfactory mucosa cells–Implications for Alzheimer's disease

L Mussalo, R Lampinen, S Avesani, T Závodná… - Redox biology, 2024 - Elsevier
Constituents of air pollution, the ultrafine particles (UFP) with a diameter of≤ 0.1 μm, are
considerably related to traffic emissions. Several studies link air pollution to Alzheimer's …