Context: Male cancer patients suffer from fatigue, sexual dysfunction, and decreased
functional performance and muscle mass. These symptoms are seen in men with …

Introduction: Interstitial lung disease (ILD) is an adverse drug reaction (ADR) of concern in
Japanese patients with non–small-cell lung cancer (NSCLC) receiving erlotinib. To …

To study epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) resistance
mechanisms, we established a novel gefitinib-resistant lung cancer cell line derived from an …

Background: Cytotoxic T lymphocyte antigen 4 (CTLA-4) is a potent immunoregulatory
molecule that suppresses antitumor response by downregulating T cell activation. The most …

Although a well-established risk factor for lung cancer, the impact of smoking on the survival
of non-small cell lung cancer (NSCLC) is not well known. We performed a retrospective …

Objectives Non-small cell lung cancer (NSCLC) patients who have clinically no mediastinal
lymph node metastasis but have distant metastasis are occasionally found in clinical …

Cancer patients undergo routine clinical monitoring with an array of blood tests that may
carry long‐term prognostic information. We aimed to develop a new prognostic model …

Purpose: To investigate the prognostic value of weight loss before diagnosis in patients with
advanced stage non-small cell lung cancer (NSCLC) treated with first-line chemotherapy …

Background: Lung cancer was one of the most common cancers in both men and women all
over the world. In this study, we aimed to clarify who could survive after long term …

Background/Aim: The prognostic role of thyroid transcription factor-1 (TTF1) in advanced
lung cancer is not clearly established. The present study aimed to evaluate the associations …