Peptide-based supramolecular systems chemistry seeks to mimic the ability of life forms to
use conserved sets of building blocks and chemical reactions to achieve a bewildering array …

Despite advances in machine learning-based protein structure prediction, we are still far
from fully understanding how proteins fold into their native conformation. The conventional …

The fundamental roles that peptides and proteins play in today's biology makes it almost
indisputable that peptides were key players in the origin of life. Insofar as it is appropriate to …

Chirality is one of the most important structural features in biological systems. Peptides, as a
class of small biomolecules, can self-assemble into various chiral supramolecular polymers …

Lipopeptides are amphiphilic peptides in which an aliphatic chain is attached to either the C
or N terminus of peptides. Their self-assembly—into micelles, vesicles, nanotubes, fibres or …

In diverse natural enzyme systems, their elegant properties and functions appeal to great
interest not only in unraveling the natural profound mystery but also in engineering the …

Enzymes play vital roles in cellular functions by catalyzing biochemical reactions in high
activity and selectivity, which is largely attributed to the cooperation between the exquisitely …

Peptides and their conjugates (to lipids, bulky N-terminals, or other groups) can self-
assemble into nanostructures such as fibrils, nanotubes, coiled coil bundles, and micelles …

The self‐assembly of short peptides gives rise to versatile nanoassemblies capable of
promoting efficient catalysis. We have semi‐rationally designed a series of seven‐residue …

Fluorinated compounds, while rarely used by nature, are emerging as fundamental
ingredients in biomedical research, with applications in drug discovery, metabolomics …