Single particle tracking: from theory to biophysical applications

H Shen, LJ Tauzin, R Baiyasi, W Wang… - Chemical …, 2017 - ACS Publications
After three decades of developments, single particle tracking (SPT) has become a powerful
tool to interrogate dynamics in a range of materials including live cells and novel catalytic …

Single-virus tracking: from imaging methodologies to virological applications

SL Liu, ZG Wang, HY Xie, AA Liu, DC Lamb… - Chemical …, 2020 - ACS Publications
Uncovering the mechanisms of virus infection and assembly is crucial for preventing the
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …

An alternative to MINFLUX that enables nanometer resolution in a confocal microscope

LA Masullo, AM Szalai, LF Lopez, M Pilo-Pais… - Light: Science & …, 2022 - nature.com
Localization of single fluorescent emitters is key for physicochemical and biophysical
measurements at the nanoscale and beyond ensemble averaging. Examples include single …

Simultaneous nanorheometry and nanothermometry using intracellular diamond quantum sensors

Q Gu, L Shanahan, JW Hart, S Belser, N Shofer… - ACS …, 2023 - ACS Publications
The viscoelasticity of the cytoplasm plays a critical role in cell morphology, cell division, and
intracellular transport. Viscoelasticity is also interconnected with other biophysical …

Axial de-scanning using remote focusing in the detection arm of light-sheet microscopy

H Dibaji, A Kazemi Nasaban Shotorban… - Nature …, 2024 - nature.com
Rapid, high-resolution volumetric imaging without moving heavy objectives or disturbing
delicate samples remains challenging. Pupil-matched remote focusing offers a promising …

High-resolution low-power hyperspectral line-scan imaging of fast cellular dynamics using azo-enhanced Raman scattering probes

Y Yu, Y Tang, K Chu, T Gao… - Journal of the American …, 2022 - ACS Publications
Small-molecule Raman probes for cellular imaging have attracted great attention owing to
their sharp peaks that are sensitive to environmental changes. The small cross section of …

Opportunities for diamond quantum metrology in biological systems

S Belser, J Hart, Q Gu, L Shanahan… - Applied Physics …, 2023 - pubs.aip.org
Sensors that harness quantum mechanical effects can enable high sensitivity and high
spatial resolution probing of their environment. The nitrogen-vacancy defect in diamond, a …

[HTML][HTML] A common framework for single-molecule localization using sequential structured illumination

LA Masullo, LF Lopez, FD Stefani - Biophysical Reports, 2022 - cell.com
Localization of single fluorescent molecules is key for physicochemical and biophysical
measurements, such as single-molecule tracking and super-resolution imaging by single …

Principles and applications of single particle tracking in cell research

Z Wang, X Wang, Y Zhang, W Xu, X Han - Small, 2021 - Wiley Online Library
It is a tough challenge for many decades to decipher the complex relationships between cell
behaviors and cellular physical properties. Single particle tracking (SPT) with high spatial …

3D motion of vesicles along microtubules helps them to circumvent obstacles in cells

I Verdeny-Vilanova, F Wehnekamp… - Journal of cell …, 2017 - journals.biologists.com
Vesicle transport is regulated at multiple levels, including regulation by scaffolding proteins
and the cytoskeleton. This tight regulation is essential, since slowing or stoppage of …