The concept of two types of alpha-adrenoceptor, alpha 1 located on smooth muscle and
mediating contraction and alpha 2 located on nerve terminals and mediating inhibition of …

Cone snails use venom containing a cocktail of peptides ('conopeptides') to capture their
prey. Many of these peptides also target mammalian receptors, often with exquisite …

There are currently some experimental observations which point toward a new classification
of alpha-adrenoceptors, not only in terms of the recognition site, but also as initiators of …

The contractile response of the guinea‐pig vas deferens to tetanic nerve stimulation was
biphasic. The first phase was mimicked by exogenously applied ATP. The second more …

The contractile response of the guinea pig vas deferens to motor nerve stimulation is
biphasic. The first phase is antagonized by the specific adenosine triphosphate-receptor …

Pig isolated renal arteries contract in response to addition of noradrenaline, 5-
hydroxytryptamine, histamine, angiotensin II, vasopressin and carbachol, whereas …

We have recorded the responses of arteriolar smooth muscle cells to iontophoretically
applied noradrenaline. Records of both muscle movement and muscle membrane potential …

Twitch contractions of the rabbit vas deferens elicited field stimulation were inhibited by
tetrodotoxin, guanethidine, bretylium and α, ß-methylene-ATP but were unaffected by …

Concomitant release of noradrenaline (NA)(using tritium labelling), adenosine 5′-
triphosphate (ATP)(using the luciferin-luciferase firefly technique) and neuropeptide Y (using …

Vasopressin was among the first mammalian hormonal peptides to be identified and to have
its structure determined1. Its only undisputed physiological role is as a circulating …