New developments in RiPP discovery, enzymology and engineering
M Montalbán-López, TA Scott, S Ramesh… - Natural product …, 2021 - pubs.rsc.org
Covering: up to June 2020 Ribosomally-synthesized and post-translationally modified
peptides (RiPPs) are a large group of natural products. A community-driven review in 2013 …
peptides (RiPPs) are a large group of natural products. A community-driven review in 2013 …
Fungal secondary metabolism: regulation, function and drug discovery
NP Keller - Nature Reviews Microbiology, 2019 - nature.com
One of the exciting movements in microbial sciences has been a refocusing and
revitalization of efforts to mine the fungal secondary metabolome. The magnitude of …
revitalization of efforts to mine the fungal secondary metabolome. The magnitude of …
Mining genomes to illuminate the specialized chemistry of life
All organisms produce specialized organic molecules, ranging from small volatile chemicals
to large gene-encoded peptides, that have evolved to provide them with diverse cellular and …
to large gene-encoded peptides, that have evolved to provide them with diverse cellular and …
Taxonomy of Aspergillus section Flavi and their production of aflatoxins, ochratoxins and other mycotoxins
JC Frisvad, V Hubka, CN Ezekiel, SB Hong… - Studies in …, 2019 - ingentaconnect.com
Aflatoxins and ochratoxins are among the most important mycotoxins of all and producers of
both types of mycotoxins are present in Aspergillus section Flavi, albeit never in the same …
both types of mycotoxins are present in Aspergillus section Flavi, albeit never in the same …
Enzymatic carbon–sulfur bond formation in natural product biosynthesis
KL Dunbar, DH Scharf, A Litomska… - Chemical …, 2017 - ACS Publications
Sulfur plays a critical role for the development and maintenance of life on earth, which is
reflected by the wealth of primary metabolites, macromolecules, and cofactors bearing this …
reflected by the wealth of primary metabolites, macromolecules, and cofactors bearing this …
Safety of the fungal workhorses of industrial biotechnology: update on the mycotoxin and secondary metabolite potential of Aspergillus niger, Aspergillus oryzae, and …
JC Frisvad, LLH Møller, TO Larsen, R Kumar… - Applied Microbiology …, 2018 - Springer
This review presents an update on the current knowledge of the secondary metabolite
potential of the major fungal species used in industrial biotechnology, ie, Aspergillus niger …
potential of the major fungal species used in industrial biotechnology, ie, Aspergillus niger …
Biologically active secondary metabolites from the fungi
Many Fungi have a well-developed secondary metabolism. The diversity of fungal species
and the diversification of biosynthetic gene clusters underscores a nearly limitless potential …
and the diversification of biosynthetic gene clusters underscores a nearly limitless potential …
Anti-tubulin agents of natural origin: Targeting taxol, vinca, and colchicine binding domains
Microtubules are a protein which is made of α-and β-heterodimer. It is one of the main
components of the cell which play a vital role in cell division especially in G2/M-phase. It …
components of the cell which play a vital role in cell division especially in G2/M-phase. It …
The birth, evolution and death of metabolic gene clusters in fungi
Fungi contain a remarkable diversity of both primary and secondary metabolic pathways
involved in ecologically specialized or accessory functions. Genes in these pathways are …
involved in ecologically specialized or accessory functions. Genes in these pathways are …
P450-modified ribosomally synthesized peptides with aromatic cross-links
YL Hu, FZ Yin, J Shi, SY Ma, ZR Wang… - Journal of the …, 2023 - ACS Publications
Cyclization of linear peptides is an effective strategy to convert flexible molecules into rigid
compounds, which is of great significance for enhancing the peptide stability and bioactivity …
compounds, which is of great significance for enhancing the peptide stability and bioactivity …