The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemia
AS Sperling, CJ Gibson, BL Ebert - Nature Reviews Cancer, 2017 - nature.com
Myelodysplastic syndrome (MDS) is a clonal disease that arises from the expansion of
mutated haematopoietic stem cells. In a spectrum of myeloid disorders ranging from clonal …
mutated haematopoietic stem cells. In a spectrum of myeloid disorders ranging from clonal …
Diagnosis and treatment of primary myelodysplastic syndromes in adults: recommendations from the European LeukemiaNet
L Malcovati, E Hellström-Lindberg… - Blood, The Journal …, 2013 - ashpublications.org
Within the myelodysplastic syndrome (MDS) work package of the European LeukemiaNet,
an Expert Panel was selected according to the framework elements of the National Institutes …
an Expert Panel was selected according to the framework elements of the National Institutes …
The use of immunosuppressive therapy in MDS: clinical outcomes and their predictors in a large international patient cohort
Most studies of immunosuppressive therapy (IST) in myelodysplastic syndromes (MDS) are
limited by small numbers and their single-center nature, and report conflicting data …
limited by small numbers and their single-center nature, and report conflicting data …
Factors affecting response and survival in patients with myelodysplasia treated with immunosuppressive therapy
Purpose Marrow failure in some patients with myelodysplastic syndrome (MDS) responds to
immunosuppressive treatment (IST), but long-term outcome after IST has not been …
immunosuppressive treatment (IST), but long-term outcome after IST has not been …
Immunosuppressive therapy for patients with myelodysplastic syndrome: a prospective randomized multicenter phase III trial comparing antithymocyte globulin plus …
JR Passweg, AAN Giagounidis, M Simcock… - Journal of clinical …, 2011 - ascopubs.org
Purpose Immunosuppressive treatment is reported to improve cytopenia in some patients
with myelodysplastic syndrome (MDS). Combined antithymocyte globulin (ATG) and …
with myelodysplastic syndrome (MDS). Combined antithymocyte globulin (ATG) and …
Reduced natural killer (NK) function associated with high-risk myelodysplastic syndrome (MDS) and reduced expression of activating NK receptors
PK Epling-Burnette, F Bai, JS Painter… - Blood, The Journal …, 2007 - ashpublications.org
Myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis with
potential for progression to acute myeloid leukemia (AML). We compared natural killer (NK) …
potential for progression to acute myeloid leukemia (AML). We compared natural killer (NK) …
Type 1 diabetes: current concepts in epidemiology, pathophysiology, clinical care, and research
MJ Gan, A Albanese-O'Neill, MJ Haller - Current problems in pediatric and …, 2012 - Elsevier
Type 1 diabetes (T1D) is an autoimmune disease mediated by a combination of genetic and
environmental triggers resulting in lymphocytic infiltration of pancreatic islets, destruction of …
environmental triggers resulting in lymphocytic infiltration of pancreatic islets, destruction of …
The myelodysplastic syndromes: diagnosis and treatment
DP Steensma, JM Bennett - Mayo Clinic Proceedings, 2006 - Elsevier
The myelodysplastic syndromes (MDSs) are common, acquired, clinically challenging
hematologic conditions that are characterized by bone marrow failure and a risk of …
hematologic conditions that are characterized by bone marrow failure and a risk of …
A simple method to predict response to immunosuppressive therapy in patients with myelodysplastic syndrome
Y Saunthararajah, R Nakamura, R Wesley, QJ Wang… - Blood, 2003 - ashpublications.org
Immunosuppression with antithymocyte globulin (ATG) or cyclosporine (CSA) can be used
to treat the cytopenia associated with myelodysplastic syndrome (MDS). Previously, we …
to treat the cytopenia associated with myelodysplastic syndrome (MDS). Previously, we …
Preferential suppression of trisomy 8 compared with normal hematopoietic cell growth by autologous lymphocytes in patients with trisomy 8 myelodysplastic syndrome
EM Sloand, L Mainwaring, M Fuhrer, S Ramkissoon… - Blood, 2005 - ashpublications.org
Clinical observations and experimental evidence link bone marrow failure in
myelodysplastic syndrome (MDS) with a T cell–dominated autoimmune process …
myelodysplastic syndrome (MDS) with a T cell–dominated autoimmune process …