Plasmodium species: master renovators of their host cells

TF de Koning-Ward, MWA Dixon, L Tilley… - Nature Reviews …, 2016 - nature.com
Plasmodium parasites, the causative agents of malaria, have developed elaborate
strategies that they use to survive and thrive within different intracellular environments …

Malaria parasite proteins that remodel the host erythrocyte

AG Maier, BM Cooke, AF Cowman… - Nature Reviews …, 2009 - nature.com
Exported proteins of the malaria parasite Plasmodium falciparum interact with proteins of the
erythrocyte membrane and induce substantial changes in the morphology, physiology and …

A newly discovered protein export machine in malaria parasites

TF de Koning-Ward, PR Gilson, JA Boddey, M Rug… - Nature, 2009 - nature.com
Several hundred malaria parasite proteins are exported beyond an encasing vacuole and
into the cytosol of the host erythrocyte, a process that is central to the virulence and viability …

Targeting malaria virulence and remodeling proteins to the host erythrocyte

M Marti, RT Good, M Rug, E Knuepfer, AF Cowman - Science, 2004 - science.org
To establish infection in the host, malaria parasites export remodeling and virulence proteins
into the erythrocyte. These proteins can traverse a series of membranes, including the …

A host-targeting signal in virulence proteins reveals a secretome in malarial infection

NL Hiller, S Bhattacharjee, C Van Ooij, K Liolios… - Science, 2004 - science.org
Malaria parasites secrete proteins across the vacuolar membrane into the erythrocyte,
inducing modifications linked to disease and parasite survival. We identified an 11–amino …

[HTML][HTML] Exported proteins required for virulence and rigidity of Plasmodium falciparum-infected human erythrocytes

AG Maier, M Rug, MT O'Neill, M Brown, S Chakravorty… - Cell, 2008 - cell.com
A major part of virulence for Plasmodium falciparum malaria infection, the most lethal
parasitic disease of humans, results from increased rigidity and adhesiveness of infected …

Analysis of the Plasmodium falciparum proteome by high-accuracy mass spectrometry

E Lasonder, Y Ishihama, JS Andersen, AMW Vermunt… - Nature, 2002 - nature.com
The annotated genomes of organisms define a 'blueprint'of their possible gene products.
Post-genome analyses attempt to confirm and modify the annotation and impose a sense of …

[HTML][HTML] Lineage-specific expansion of proteins exported to erythrocytes in malaria parasites

TJ Sargeant, M Marti, E Caler, JM Carlton, K Simpson… - Genome biology, 2006 - Springer
Abstract Background The apicomplexan parasite Plasmodium falciparum causes the most
severe form of malaria in humans. After invasion into erythrocytes, asexual parasite stages …

A Plasmodium berghei reference line that constitutively expresses GFP at a high level throughout the complete life cycle

B Franke-Fayard, H Trueman, J Ramesar… - Molecular and …, 2004 - Elsevier
Green fluorescent protein (GFP) is a well-established reporter protein for the examination of
biological processes. This report describes a recombinant Plasmodium berghei …

Localization of organellar proteins in Plasmodium falciparum using a novel set of transfection vectors and a new immunofluorescence fixation method

CJ Tonkin, GG van Dooren, TP Spurck… - Molecular and …, 2004 - Elsevier
The apicoplast and mitochondrion of the malaria parasite Plasmodium falciparum are
important intracellular organelles and targets of several anti-malarial drugs. In recent years …