Plasmodium species: master renovators of their host cells
Plasmodium parasites, the causative agents of malaria, have developed elaborate
strategies that they use to survive and thrive within different intracellular environments …
strategies that they use to survive and thrive within different intracellular environments …
Malaria parasite proteins that remodel the host erythrocyte
Exported proteins of the malaria parasite Plasmodium falciparum interact with proteins of the
erythrocyte membrane and induce substantial changes in the morphology, physiology and …
erythrocyte membrane and induce substantial changes in the morphology, physiology and …
A newly discovered protein export machine in malaria parasites
Several hundred malaria parasite proteins are exported beyond an encasing vacuole and
into the cytosol of the host erythrocyte, a process that is central to the virulence and viability …
into the cytosol of the host erythrocyte, a process that is central to the virulence and viability …
Targeting malaria virulence and remodeling proteins to the host erythrocyte
To establish infection in the host, malaria parasites export remodeling and virulence proteins
into the erythrocyte. These proteins can traverse a series of membranes, including the …
into the erythrocyte. These proteins can traverse a series of membranes, including the …
A host-targeting signal in virulence proteins reveals a secretome in malarial infection
Malaria parasites secrete proteins across the vacuolar membrane into the erythrocyte,
inducing modifications linked to disease and parasite survival. We identified an 11–amino …
inducing modifications linked to disease and parasite survival. We identified an 11–amino …
[HTML][HTML] Exported proteins required for virulence and rigidity of Plasmodium falciparum-infected human erythrocytes
A major part of virulence for Plasmodium falciparum malaria infection, the most lethal
parasitic disease of humans, results from increased rigidity and adhesiveness of infected …
parasitic disease of humans, results from increased rigidity and adhesiveness of infected …
Analysis of the Plasmodium falciparum proteome by high-accuracy mass spectrometry
E Lasonder, Y Ishihama, JS Andersen, AMW Vermunt… - Nature, 2002 - nature.com
The annotated genomes of organisms define a 'blueprint'of their possible gene products.
Post-genome analyses attempt to confirm and modify the annotation and impose a sense of …
Post-genome analyses attempt to confirm and modify the annotation and impose a sense of …
[HTML][HTML] Lineage-specific expansion of proteins exported to erythrocytes in malaria parasites
Abstract Background The apicomplexan parasite Plasmodium falciparum causes the most
severe form of malaria in humans. After invasion into erythrocytes, asexual parasite stages …
severe form of malaria in humans. After invasion into erythrocytes, asexual parasite stages …
A Plasmodium berghei reference line that constitutively expresses GFP at a high level throughout the complete life cycle
B Franke-Fayard, H Trueman, J Ramesar… - Molecular and …, 2004 - Elsevier
Green fluorescent protein (GFP) is a well-established reporter protein for the examination of
biological processes. This report describes a recombinant Plasmodium berghei …
biological processes. This report describes a recombinant Plasmodium berghei …
Localization of organellar proteins in Plasmodium falciparum using a novel set of transfection vectors and a new immunofluorescence fixation method
CJ Tonkin, GG van Dooren, TP Spurck… - Molecular and …, 2004 - Elsevier
The apicoplast and mitochondrion of the malaria parasite Plasmodium falciparum are
important intracellular organelles and targets of several anti-malarial drugs. In recent years …
important intracellular organelles and targets of several anti-malarial drugs. In recent years …