Conserved double translation initiation site for Δ160p53 protein Hints at Isoform's Key role in mammalian Physiology
MJ López-Iniesta, SN Parkar, AC Ramalho… - International Journal of …, 2022 - mdpi.com
p53 is the most commonly mutated gene in human cancers. Two fundamental reasons for
this are its long protein isoforms protect from cancer, while its shorter C-terminal isoforms …
this are its long protein isoforms protect from cancer, while its shorter C-terminal isoforms …
Internal Translation of p53 Oncoproteins During Integrated Stress Response Confers Survival Advantage on Cancer Cells
MJ López-Iniesta, R Lacerda, AC Ramalho, SN Parkar… - bioRxiv, 2023 - biorxiv.org
Abstract p53 is the most known and studied tumour suppressor gene. Yet we have recently
shown that p53 is also a proto-oncogene, as it encodes the Δ160p53 oncoprotein …
shown that p53 is also a proto-oncogene, as it encodes the Δ160p53 oncoprotein …