The regulation of body temperature is one of the most critical functions of the nervous
system. Here we review our current understanding of thermoregulation in mammals. We …

Maintenance of a homeostatic body core temperature is a critical brain function
accomplished by a central neural network. This orchestrates a complex behavioral and …

Various environmental stressors, such as extreme temperatures (hot and cold), pathogens,
predators and insufficient food, can threaten life. Remarkable progress has recently been …

Neurons in the spinal dorsal horn process sensory information, which is then transmitted to
several brain regions, including those responsible for pain perception. The dorsal horn …

The lateral parabrachial nucleus (lPBN) is a major target of spinal projection neurons
conveying nociceptive input into supraspinal structures. However, the functional role of …

Body temperature regulation is a fundamental homeostatic function that is governed by the
central nervous system in homeothermic animals, including humans. The central …

Central neural circuits orchestrate a homeostatic repertoire to maintain body temperature
during environmental temperature challenges and to alter body temperature during the …

C‐fos is a proto‐oncogene that is expressed within some neurons following depolarization.
The protein product, c‐fos protein, can be identified by immunohistochemical techniques …

▪ Abstract The overall organization of the peripheral autonomic nervous system has been
known for many decades, but the mechanisms by which it is controlled by the central …

Defending body temperature against environmental thermal challenges is one of the most
fundamental homeostatic functions that are governed by the nervous system. Here we …