The continued evolution of biomedical nanotechnology has enabled clinicians to better
detect, prevent, manage, and treat human disease. In order to further push the limits of …

Immunity to pathogens critically requires pattern-recognition receptors (PRRs) to trigger
intracellular signaling cascades that initiate and direct innate and adaptive immune …

Dendritic cell (DC)-based vaccination for cancer treatment has seen considerable
development over recent decades. However, this field is currently in a state of flux toward …

One major challenge in nanomedicine is the selective delivery of nanoparticles to diseased
tissues. Nanoparticle delivery systems require targeting for specific delivery to pathogenic …

Tumor‐associated macrophages (TAMs) are a complex and heterogeneous population of
cells within the tumor microenvironment. In many tumor types, TAMs contribute toward tumor …

Dendritic-cells (DCs) have received considerable attention as potential targets for the
development of anticancer vaccines. DC-based anticancer vaccination relies on patient …

Innate sensors play a critical role in the early innate immune responses to invading
pathogens through sensing of diverse biochemical signatures also known as pathogen …

C-type lectin receptors (CLRs) represent a large receptor family including collectins,
selectins, lymphocyte lectins, and proteoglycans. CLRs share a structurally homologous …

Dendritic cells (DCs) are highly specialized antigen presenting cells of the immune system
which play a key role in regulating immune responses. Depending on the method of antigen …

Cancer remains a leading cause of death worldwide due to the lack of safer and more
effective therapies. Cancer vaccines developed from neoantigens are an emerging strategy …