It is well established that water plays a very important role in the functioning of biological
molecules and their assemblies. Among such molecular assemblies are biological …

SNARE proteins and synaptotagmin are key components of the complex machinery that
controls Ca 2+-triggered neurotransmitter release but their mechanisms of action are under …

The specific interaction of cations—particularly divalent cations—with biological membranes
is essential not only for the structure, dynamics, and stability of membranes, but also for the …

Abstract Thirty years ago, Klaus Arnold and others showed that the action of PEG in
promoting cell–cell fusion was not due to such effects as surface absorption, cross-linking …

Alzheimer's disease (AD) is a highly heritable disease (with heritability up to 76%) with a
complex genetic profile of susceptibility, among which large genome-wide association …

The process of regulated exocytosis is defined by the Ca2+-triggered fusion of two apposed
membranes, enabling the release of vesicular contents. This fusion step involves a number …

The Ca 2+-triggered merger of two apposed membranes is the defining step of regulated
exocytosis. CHOL is required at critical levels in secretory vesicle membranes to enable …

Hydration and orientation of the phosphate group of dipalmitoylphosphatidylcholine (DPPC)
monolayers in the liquid-expanded (LE) phase and the liquid-condensed (LC) phase in the …

The question concerning whether all membranes fuse according to the same mechanism
has yet to be answered satisfactorily. During fusion of model membranes or viruses …

Colloidal drug delivery systems present a range of therapeutic benefits in the treatment of a
number of challenging conditions, allowing researchers to cross barriers that have …