Surgical resection of solid tumors is currently the gold standard and preferred therapeutic
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …

Molecular imaging is revolutionizing the way we study the inner workings of the human
body, diagnose diseases, approach drug design, and assess therapies. The field as a whole …

The development of multifunctional agents for simultaneous tumor targeting and near
infrared (NIR) fluorescence imaging is expected to have significant impact on future …

Stimuli-responsive nanomaterials are increasingly important in a variety of applications such
as biosensing, molecular imaging, drug delivery and tissue engineering. For cancer …

In vivo medical imaging has made great progress due to advances in the engineering of
imaging devices and developments in the chemistry of imaging probes. Several modalities …

Molecular imaging often relies on the use of targeted and activatable reporters to quantitate
and visualize targets, biological processes, and cells in vivo. The use of optical probes with …

We have witnessed rapid development of fluorescence molecular imaging of solid tumors for
cancer diagnosis and image-guided surgery in the past decade. Many biomarkers unique to …

Despite technical advances in many areas of diagnostic radiology, the detection and
imaging of human cancer remains poor. A meaningful impact on cancer screening, staging …

Aberrant epidermal growth factor receptor (EGFR) signaling is common in cancer. Increased
expression of wild type and mutant EGFR is a widespread feature of diverse types of cancer …

Fluorescent compounds based on synthetic small molecules are powerful tools to visualize
biological events in living cells and organisms. Ever since the discovery of organic …