[HTML][HTML] Completing genome replication outside of S phase
R Bhowmick, ID Hickson, Y Liu - Molecular Cell, 2023 - cell.com
Mitotic DNA synthesis (MiDAS) is an unusual form of DNA replication that occurs during
mitosis. Initially, MiDAS was characterized as a process associated with intrinsically …
mitosis. Initially, MiDAS was characterized as a process associated with intrinsically …
The pan-genome of Aspergillus fumigatus provides a high-resolution view of its population structure revealing high levels of lineage-specific diversity driven by …
Aspergillus fumigatus is a deadly agent of human fungal disease where virulence
heterogeneity is thought to be at least partially structured by genetic variation between …
heterogeneity is thought to be at least partially structured by genetic variation between …
Segmentation, tracking and cell cycle analysis of live-cell imaging data with Cell-ACDC
F Padovani, B Mairhörmann, P Falter-Braun… - BMC biology, 2022 - Springer
Background High-throughput live-cell imaging is a powerful tool to study dynamic cellular
processes in single cells but creates a bottleneck at the stage of data analysis, due to the …
processes in single cells but creates a bottleneck at the stage of data analysis, due to the …
Mitotic chromosome condensation resets chromatin to safeguard transcriptional homeostasis during interphase
L Ramos-Alonso, P Holland… - Proceedings of the …, 2023 - National Acad Sciences
Mitotic entry correlates with the condensation of the chromosomes, changes in histone
modifications, exclusion of transcription factors from DNA, and the broad downregulation of …
modifications, exclusion of transcription factors from DNA, and the broad downregulation of …
Complete sequences of Schizosaccharomyces pombe subtelomeres reveal multiple patterns of genome variation
Y Oizumi, T Kaji, S Tashiro, Y Takeshita, Y Date… - Nature …, 2021 - nature.com
Genome sequences have been determined for many model organisms; however, repetitive
regions such as centromeres, telomeres, and subtelomeres have not yet been sequenced …
regions such as centromeres, telomeres, and subtelomeres have not yet been sequenced …
Senescence in yeast is associated with amplified linear fragments of chromosome XII rather than ribosomal DNA circle accumulation
A Zylstra, H Hadj-Moussa, D Horkai, AJ Whale… - PLoS …, 2023 - journals.plos.org
The massive accumulation of extrachromosomal ribosomal DNA circles (ERCs) in yeast
mother cells has been long cited as the primary driver of replicative ageing. ERCs arise …
mother cells has been long cited as the primary driver of replicative ageing. ERCs arise …
Life in plastic, it's fantastic! How Leishmania exploit genome instability to shape gene expression
Leishmania are kinetoplastid pathogens that cause leishmaniasis, a debilitating and
potentially life-threatening infection if untreated. Unusually, Leishmania regulate their gene …
potentially life-threatening infection if untreated. Unusually, Leishmania regulate their gene …
Dealing with DNA lesions: When one cell cycle is not enough
A Lezaja, M Altmeyer - Current opinion in cell biology, 2021 - Elsevier
Subversion of genome integrity fuels cellular adaptation and is a prerequisite for organismal
evolution, yet genomic lesions are also the harmful driving force of cancer and other age …
evolution, yet genomic lesions are also the harmful driving force of cancer and other age …
Ribosomal DNA replication time coordinates completion of genome replication and anaphase in yeast
EX Kwan, GM Alvino, KL Lynch, PF Levan… - Cell reports, 2023 - cell.com
Timely completion of genome replication is a prerequisite for mitosis, genome integrity, and
cell survival. A challenge to this timely completion comes from the need to replicate the …
cell survival. A challenge to this timely completion comes from the need to replicate the …