Summary Since 1989, 18 second-generation antiseizure medications have reached the
market, resulting in a greatly increased range of treatment options for patients and …

ABSTRACT Introduction: Antiepileptic drugs (AEDs) are the cornerstone of treatment of
patients with epilepsy, and there are presently 27 licensed AEDs making AEDs among the …

Women with epilepsy (WWE) wishing for a child represent a highly relevant subgroup of
epilepsy patients. The treating epileptologist needs to delineate the epilepsy syndrome and …

During pregnancy, the pharmacokinetics of an antiepileptic drug is altered because of
changes in the clearance capacity and volume of distribution. These changes may have …

Epilepsy is a group of neurological diseases characterized by susceptibility to recurrent
seizures. Antiseizure medications (ASMs) are the mainstay of treatment, but many …

Introduction: Pregnancy-related physiological changes exert a crucial impact on the
pharmacokinetics of antidepressants; however, the current evidence presents …

An estimated 60 million people worldwide suffer from epilepsy, half of whom are women.
About one-third of women with epilepsy are of childbearing age. The childbirth rate in …

Background Levetiracetam has been widely used as a treatment option for different types of
epilepsy in both adults and children. Because of its large between-subject variability, several …

Objectives To compare the efficacy and safety of levetiracetam and phenytoin for the
treatment of established status epilepticus. Methods In this systematic review, we searched …

Background Seizures are the main cause of maternal death in women with epilepsy, but
there are no tools for predicting seizures in pregnancy. We set out to develop and validate a …