The genetic basis of obesity and related metabolic diseases in humans and companion animals
N Wallis, E Raffan - Genes, 2020 - mdpi.com
Obesity is one of the most prevalent health conditions in humans and companion animals
globally. It is associated with premature mortality, metabolic dysfunction, and multiple health …
globally. It is associated with premature mortality, metabolic dysfunction, and multiple health …
Animal models for the study of the relationships between diet and obesity: a focus on dietary protein and estrogen deficiency
T Chalvon-Demersay, F Blachier, D Tomé… - Frontiers in …, 2017 - frontiersin.org
Obesity is an increasing major public health concern asking for dietary strategies to limit
weight gain and associated comorbidities. In this review, we present animal models …
weight gain and associated comorbidities. In this review, we present animal models …
Frequency, breed predisposition and demographic risk factors for overweight status in dogs in the UK
C Pegram, E Raffan, E White… - Journal of Small …, 2021 - Wiley Online Library
Objectives To evaluate the prevalence and risk factors for overweight status in dogs under
primary veterinary care in the UK. Materials and Methods A retrospective study design was …
primary veterinary care in the UK. Materials and Methods A retrospective study design was …
Analysis of large versus small dogs reveals three genes on the canine X chromosome associated with body weight, muscling and back fat thickness
J Plassais, M Rimbault, FJ Williams, BW Davis… - PLoS …, 2017 - journals.plos.org
Domestic dog breeds display significant diversity in both body mass and skeletal size,
resulting from intensive selective pressure during the formation and maintenance of modern …
resulting from intensive selective pressure during the formation and maintenance of modern …
Genetic marker discovery in complex traits: a field example on fat content and composition in pigs
Among the large number of attributes that define pork quality, fat content and composition
have attracted the attention of breeders in the recent years due to their interaction with …
have attracted the attention of breeders in the recent years due to their interaction with …
Hypercaloric diet-induced obesity and obesity-related metabolic disorders in experimental models
N Pinheiro-Castro, LBAR Silva, GM Novaes… - Reviews on Biomarker …, 2019 - Springer
Overnutrition and obesity have developed into a major public health problem across
different parts of the world. Epidemiological studies have shown that excessive intake of …
different parts of the world. Epidemiological studies have shown that excessive intake of …
The importance of the nuclear positioning of the PPARG gene for its expression during porcine in vitro adipogenesis
Proper expression of the PPARG gene, which encodes a key transcription factor of
adipogenesis, is indispensable in the formation of mature adipocytes. The positioning of a …
adipogenesis, is indispensable in the formation of mature adipocytes. The positioning of a …
Confirmation that a deletion in the POMC gene is associated with body weight of Labrador Retriever dogs
M Mankowska, P Krzeminska, M Graczyk… - Research in veterinary …, 2017 - Elsevier
A 14-bp deletion present in the proopiomelanocortin (POMC) gene of Labrador and Flat
Coat Retrievers (FCR), but absent in POMC of other breeds, disrupts the β-MSH and β …
Coat Retrievers (FCR), but absent in POMC of other breeds, disrupts the β-MSH and β …
Identification of Signatures of Positive Selection That Have Shaped the Genomic Landscape of South African Pig Populations
NL Hlongwane, EF Dzomba, K Hadebe… - Animals, 2024 - mdpi.com
Simple Summary Pigs are important in agriculture as they produce animal-based protein for
human consumption. The analysis of selection signatures has implications for the …
human consumption. The analysis of selection signatures has implications for the …
Expression of key genes involved in DNA methylation during in vitro differentiation of porcine mesenchymal stem cells (MSCs) into adipocytes
J Stachecka, W Lemanska, M Noak… - … and Biophysical Research …, 2020 - Elsevier
The normal course of DNA methylation depends on the correct functioning of the DNA
methylation machinery, which include DNA methyltransferase enzymes (DNMTs) and methyl …
methylation machinery, which include DNA methyltransferase enzymes (DNMTs) and methyl …