Four Chromosomal Type IV Secretion Systems in Helicobacter pylori: Composition, Structure and Function

W Fischer, N Tegtmeyer, K Stingl… - Frontiers in Microbiology, 2020 - frontiersin.org
The pathogenic bacterium Helicobacter pylori is genetically highly diverse and a major risk
factor for the development of peptic ulcer disease and gastric adenocarcinoma in humans …

Biomarker Characterization and Prediction of Virulence and Antibiotic Resistance from Helicobacter pylori Next Generation Sequencing Data

JS Vital, L Tanoeiro, R Lopes-Oliveira, FF Vale - Biomolecules, 2022 - mdpi.com
The Gram-negative bacterium Helicobacter pylori colonizes ca 50% of human stomachs
worldwide and is the major risk factor for gastric adenocarcinoma. Its high genetic variability …

Virus-like transposons cross the species barrier and drive the evolution of genetic incompatibilities

SA Widen, IC Bes, A Koreshova, P Pliota, D Krogull… - Science, 2023 - science.org
Horizontal gene transfer, the movement of genetic material between species, has been
reported across all major eukaryotic lineages. However, the underlying mechanisms of …

Assessing the utility of CASP14 models for molecular replacement

C Millán, RM Keegan, J Pereira… - Proteins: Structure …, 2021 - Wiley Online Library
The assessment of CASP models for utility in molecular replacement is a measure of their
use in a valuable real‐world application. In CASP7, the metric for molecular replacement …

Modulation of membrane phosphoinositide dynamics by the phosphatidylinositide 4-kinase activity of the Legionella LepB effector

NA Dong, M Niu, L Hu, Q Yao, R Zhou, F Shao - Nature microbiology, 2016 - nature.com
Legionella pneumophila, the causative bacterium for Legionnaires' disease, hijacks host
membrane trafficking for the maturation of the Legionella-containing vacuole (LCV). The …

Evodiamine Inhibits Helicobacter pylori Growth and Helicobacter pylori-Induced Inflammation

JY Yang, JB Kim, P Lee, SH Kim - International Journal of Molecular …, 2021 - mdpi.com
Helicobacter pylori (H. pylori) classified as a class I carcinogen by the World Health
Organization (WHO) plays an important role in the progression of chronic gastritis and the …

Post-translational modifications of p65: state of the art

X Sun, S Cao, C Mao, F Sun, X Zhang… - Frontiers in Cell and …, 2024 - frontiersin.org
P65, a protein subunit of NF-κB, is a widely distributed transcription factor in eukaryotic cells
and exerts diverse regulatory functions. Post-translational modifications such as …

Phosphorylation of spore coat proteins by a family of atypical protein kinases

KB Nguyen, A Sreelatha, ES Durrant… - Proceedings of the …, 2016 - National Acad Sciences
The modification of proteins by phosphorylation occurs in all life forms and is catalyzed by a
large superfamily of enzymes known as protein kinases. We recently discovered a family of …

Inflammasome Activation by Helicobacter pylori and Its Implications for Persistence and Immunity

SK Pachathundikandi, A Müller, S Backert - Inflammasome signaling and …, 2016 - Springer
Infection with the Gram-negative pathogen Helicobacter pylori is the most prevalent chronic
bacterial infection affecting about 50% of the human world population and is the main risk …

Genomic analysis of 40 prophages located in the genomes of 16 carbapenemase-producing clinical strains of Klebsiella pneumoniae

I Bleriot, R Trastoy, L Blasco… - Microbial …, 2020 - microbiologyresearch.org
Klebsiella pneumoniae is the clinically most important species within the genus Klebsiella
and, as a result of the continuous emergence of multi-drug resistant (MDR) strains, the …