[HTML][HTML] Maximum-likelihood model fitting for quantitative analysis of SMLM data
Quantitative data analysis is important for any single-molecule localization microscopy
(SMLM) workflow to extract biological insights from the coordinates of the single …
(SMLM) workflow to extract biological insights from the coordinates of the single …
Mapping molecular complexes with super-resolution microscopy and single-particle analysis
Understanding the structure of supramolecular complexes provides insight into their
functional capabilities and how they can be modulated in the context of disease. Super …
functional capabilities and how they can be modulated in the context of disease. Super …
[HTML][HTML] MicroFPGA: An affordable FPGA platform for microscope control
Modern microscopy relies increasingly on microscope automation to improve throughput,
ensure reproducibility or observe rare events. Automation requires computer control of the …
ensure reproducibility or observe rare events. Automation requires computer control of the …
Deep-learning microscopy image reconstruction with quality control reveals second-scale rearrangements in RNA polymerase II clusters
Fluorescence microscopy, a central tool of biological research, is subject to inherent trade-
offs in experiment design. For instance, image acquisition speed can only be increased in …
offs in experiment design. For instance, image acquisition speed can only be increased in …
Load adaptation by endocytic actin networks
C Kaplan, SJ Kenny, X Chen… - Molecular biology of …, 2022 - Am Soc Cell Biol
Clathrin-mediated endocytosis (CME) robustness under elevated membrane tension is
maintained by actin assembly–mediated force generation. However, whether more actin …
maintained by actin assembly–mediated force generation. However, whether more actin …
Automated 3D multi-color single-molecule localization microscopy
Since its inception, single molecule localization microscopy (SMLM) has enabled imaging
scientists to visualize biological structures with unprecedented resolution. Particularly …
scientists to visualize biological structures with unprecedented resolution. Particularly …
The morphological role of ligand inhibitors in blocking receptor-and clathrin-mediated endocytosis
D Agostinelli, GJ Elfring, M Bacca - Soft Matter, 2022 - pubs.rsc.org
Cells often internalize particles through endocytic pathways that involve the binding
between cell receptors and particle ligands, which drives the cell membrane to wrap the …
between cell receptors and particle ligands, which drives the cell membrane to wrap the …
Super-resolution microscopy of the synaptonemal complex within the Caenorhabditis elegans germline
I Čavka, RM Power, D Walsh, T Zimmermann… - JoVE (Journal of …, 2022 - jove.com
During meiosis, homologous chromosomes must recognize and adhere to one another to
allow for their correct segregation. One of the key events that secures the interaction of …
allow for their correct segregation. One of the key events that secures the interaction of …
Multiplexed and millimeter-scale fluorescence nanoscopy of cells and tissue sections via prism-illumination and microfluidics-enhanced DNA-PAINT
MJ Rames, JP Kenison, D Heineck… - … & Biomedical Imaging, 2023 - ACS Publications
Fluorescence nanoscopy has become increasingly powerful for biomedical research, but it
has historically afforded a small field-of-view (FOV) of around 50 μm× 50 μm at once and …
has historically afforded a small field-of-view (FOV) of around 50 μm× 50 μm at once and …
[PDF][PDF] Multiplexed and millimeter-scale superresolution imaging of cells and tissue sections via prism-illumination and microfluidics-enhanced DNA-PAINT
Superresolution microscopy (SRM) has been an enabling tool for biomedical research. A
major limitation of SRM, however, is the small field-of-view (FOV), typically~ 50µm x 50µm …
major limitation of SRM, however, is the small field-of-view (FOV), typically~ 50µm x 50µm …