Cyclic olefin polymers (COPs) are increasingly popular as substrate material for
microfluidics. This is due to their promising properties, such as high chemical resistance, low …

Over the past twenty years, the field of microfluidics has emerged providing one of the main
enabling technologies to realize miniaturized chemical analysis systems, often referred to as …

Extracellular vesicles (EVs) are recognized as next generation diagnostic biomarkers due to
their disease‐specific biomolecular cargoes and importance in cell–cell communications. A …

We report on the possibility to achieve ultra high efficiencies (order of 1 million theoretical
plates) in liquid chromatography in a relatively short time of 20 min (elution time of …

Microfluidics is a platform technology that has been used for genomics, proteomics,
chemical synthesis, environment monitoring, cellular studies, and other applications. The …

Cyclo-olefin polymer (COP) surfaces are micro–nanotextured using O 2 plasma chemistry in
one-step process. These surfaces subsequently display multiple functionality,(A) they are …

Miniaturization of liquid chromatography (LC) is at the leading edge of the research topics
and offers a wide range of applications in chemistry, biology, pharmaceutical, clinical …

Highlights•Describes the challenges in intact protein bioanalysis by LC-MS•Describes
approaches to reduce the width of the charge-state envelope upon electrospray ionization …

LC is one of the most powerful separation techniques as illustrated by its leading role in
analytical sciences through both academic and industrial communities. Its implementation in …

Thermoplastic materials such as cyclic-olefin copolymers (COC) provide a versatile and cost-
effective alternative to the traditional glass or silicon substrate for rapid prototyping and …