Lactase persistence—the ability of adults to digest the lactose in milk—varies widely in
frequency across human populations. This trait represents an adaptation to the …

Most people are born with the ability to digest lactose, the major carbohydrate in milk and
the main source of nutrition until weaning. Approximately 75% of the world's population …

Lactase persistence (LP), the continued expression of lactase into adulthood, is the most
strongly selected single gene trait over the last 10,000 years in multiple human populations …

Background African populations provide a unique opportunity to interrogate host-microbe co-
evolution and its impact on adaptive phenotypes due to their genomic, phenotypic, and …

In the last three decades, genetic studies have played an increasingly important role in
exploring human history. They have helped to conclusively establish that anatomically …

As the ancestral homeland of our species, Africa contains elevated levels of genetic diversity
and substantial population structure. Importantly, African genomes are heterogeneous: They …

The ability to digest milk into adulthood, lactase persistence (LP), as well as specific genetic
variants associated with LP, is heterogeneously distributed in global populations [1–4] …

Background Human population history in the Holocene was profoundly impacted by
changes in lifestyle following the invention and adoption of food-production practices. These …

Drug resistance has become a threat to global health, and new interventions are needed to
control major infectious diseases. The composition of gut microbiota has been linked to …

Abstract Background. People of the Fulani ethnic group are more resistant to malaria
compared with genetically distinct ethnic groups, such as the Dogon people, in West Africa …