On the evolution of lactase persistence in humans
Lactase persistence—the ability of adults to digest the lactose in milk—varies widely in
frequency across human populations. This trait represents an adaptation to the …
frequency across human populations. This trait represents an adaptation to the …
Lactose intolerance: diagnosis, genetic, and clinical factors
R Mattar, DF de Campos Mazo… - Clinical and experimental …, 2012 - Taylor & Francis
Most people are born with the ability to digest lactose, the major carbohydrate in milk and
the main source of nutrition until weaning. Approximately 75% of the world's population …
the main source of nutrition until weaning. Approximately 75% of the world's population …
[HTML][HTML] Low prevalence of lactase persistence in Bronze Age Europe indicates ongoing strong selection over the last 3,000 years
Lactase persistence (LP), the continued expression of lactase into adulthood, is the most
strongly selected single gene trait over the last 10,000 years in multiple human populations …
strongly selected single gene trait over the last 10,000 years in multiple human populations …
Lifestyle and the presence of helminths is associated with gut microbiome composition in Cameroonians
MA Rubel, A Abbas, LJ Taylor, A Connell, C Tanes… - Genome biology, 2020 - Springer
Background African populations provide a unique opportunity to interrogate host-microbe co-
evolution and its impact on adaptive phenotypes due to their genomic, phenotypic, and …
evolution and its impact on adaptive phenotypes due to their genomic, phenotypic, and …
Tales of human migration, admixture, and selection in Africa
CM Schlebusch, M Jakobsson - Annual Review of Genomics …, 2018 - annualreviews.org
In the last three decades, genetic studies have played an increasingly important role in
exploring human history. They have helped to conclusively establish that anatomically …
exploring human history. They have helped to conclusively establish that anatomically …
[PDF][PDF] Evolutionary genetics and admixture in African populations
A Pfennig, LN Petersen, P Kachambwa… - Genome Biology and …, 2023 - academic.oup.com
As the ancestral homeland of our species, Africa contains elevated levels of genetic diversity
and substantial population structure. Importantly, African genomes are heterogeneous: They …
and substantial population structure. Importantly, African genomes are heterogeneous: They …
Lactase persistence alleles reveal partial East African ancestry of southern African Khoe pastoralists
The ability to digest milk into adulthood, lactase persistence (LP), as well as specific genetic
variants associated with LP, is heterogeneously distributed in global populations [1–4] …
variants associated with LP, is heterogeneously distributed in global populations [1–4] …
Population history and genetic adaptation of the Fulani nomads: inferences from genome-wide data and the lactase persistence trait
M Vicente, E Priehodová, I Diallo, E Podgorná… - BMC genomics, 2019 - Springer
Background Human population history in the Holocene was profoundly impacted by
changes in lifestyle following the invention and adoption of food-production practices. These …
changes in lifestyle following the invention and adoption of food-production practices. These …
Functional food for the stimulation of the immune system against malaria
T Bamgbose, AR Anvikar, P Alberdi… - Probiotics and …, 2021 - Springer
Drug resistance has become a threat to global health, and new interventions are needed to
control major infectious diseases. The composition of gut microbiota has been linked to …
control major infectious diseases. The composition of gut microbiota has been linked to …
Genetic Resistance to Malaria Is Associated With Greater Enhancement of Immunoglobulin (Ig)M Than IgG Responses to a Broad Array of Plasmodium falciparum …
Abstract Background. People of the Fulani ethnic group are more resistant to malaria
compared with genetically distinct ethnic groups, such as the Dogon people, in West Africa …
compared with genetically distinct ethnic groups, such as the Dogon people, in West Africa …