Advances in RNA-sequencing techniques have led to the discovery of thousands of non-
coding transcripts with unknown function. There are several types of non-coding linear …

Since decades it has been known that non-protein-coding RNAs have important cellular
functions. Deep sequencing recently facilitated the discovery of thousands of novel …

In recent year, increasing evidence suggests that noncoding RNAs play important roles in
the regulation of tissue homeostasis and pathophysiological conditions. Besides small …

Recent studies suggest that the majority of the human genome is transcribed, but only about
2% accounts for protein-coding exons. Long noncoding RNAs (lncRNAs) constitute a …

Epigenetic reprogramming is a critical process of pathological gene induction during cardiac
hypertrophy and remodeling, but the underlying regulatory mechanisms remain to be …

Transcription of a large part of the human genome results in RNA transcripts that have
limited or no protein-coding potential. These include long noncoding RNAs (lncRNAs) …

RNAs not encoding proteins have gained prominence over the last couple of decades as
fundamental regulators of cellular function. Not surprisingly, their dysregulation is …

Aims Circular RNA (circRNA) is a newly validated class of single-stranded RNA,
ubiquitously expressed in mammalian tissues and possessing key functions including acting …

A large part of the mammalian genome is transcribed into noncoding RNAs. Long
noncoding RNAs (lncRNAs) have emerged as critical epigenetic regulators of gene …

Vast parts of mammalian genomes encode for transcripts that are not further translated into
proteins. The purpose of the majority of such noncoding ribonucleic acids (RNAs) remained …