The immunobiology of corneal HSV-1 infection and herpetic stromal keratitis
SUMMARY Human alphaherpesvirus 1 (HSV-1) is a highly successful neurotropic pathogen
that primarily infects the epithelial cells lining the orofacial mucosa. After primary lytic …
that primarily infects the epithelial cells lining the orofacial mucosa. After primary lytic …
Small animal models to study herpes simplex virus infections
MT Hussain, BA Stanfield, DI Bernstein - Viruses, 2024 - mdpi.com
Herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) are two of the
most prevalent human viruses worldwide. They are known to cause a variety of diseases …
most prevalent human viruses worldwide. They are known to cause a variety of diseases …
Emerging drugs for the treatment of herpetic keratitis
Introduction Herpes simplex keratitis stands as a prominent factor contributing to infectious
blindness among developed nations. On a global scale, over 60% of the population tests …
blindness among developed nations. On a global scale, over 60% of the population tests …
[HTML][HTML] HerpDock: A GUI-based gateway to HSV-1 molecular docking insights
Abstract Herpes Simplex Virus 1 (HSV-1) is a member of the alpha-Herpesviridae family,
with over 60% of the global population being seropositive. HSV-1 can cause a range of …
with over 60% of the global population being seropositive. HSV-1 can cause a range of …
The opportunities and challenges of epigenetic approaches to manage herpes simplex infections
SM Saddoris, LM Schang - Expert Review of Anti-infective Therapy, 2024 - Taylor & Francis
Introduction Despite the existence of antivirals that potently and efficiently inhibit the
replication of herpes simplex virus 1 and 2 (HSV-1,− 2), their ability to establish and …
replication of herpes simplex virus 1 and 2 (HSV-1,− 2), their ability to establish and …
[HTML][HTML] Enhancement of HSV-1 cell-free virion release by the envelope protein gC
TC Frost, M Salnikov, SA Rice - Virology, 2024 - Elsevier
Glycoprotein C (gC), one of∼ 12 HSV-1 envelope glycoproteins, carries out several
important functions during infection, including the enhancement of virion attachment by …
important functions during infection, including the enhancement of virion attachment by …
A fur plucking model to study herpes simplex virus reactivation and recurrent disease
Herpes simplex viruses (HSV-1 and HSV-2) most commonly cause ulcerative epithelial
lesions (cold sores and genital herpes). Importantly, HSV establishes life-long persistent …
lesions (cold sores and genital herpes). Importantly, HSV establishes life-long persistent …
Tunneling Nanotubes: The Cables for Viral Spread and Beyond
Multicellular organisms require cell-to-cell communication to maintain homeostasis and
thrive. For cells to communicate, a network of filamentous, actin-rich tunneling nanotubes …
thrive. For cells to communicate, a network of filamentous, actin-rich tunneling nanotubes …