Chemical biology of the sugar code
HJ Gabius, HC Siebert, S André… - …, 2004 - Wiley Online Library
A high‐density coding system is essential to allow cells to communicate efficiently and
swiftly through complex surface interactions. All the structural requirements for forming a …
swiftly through complex surface interactions. All the structural requirements for forming a …
Synthesis of glycoproteins
BG Davis - Chemical reviews, 2002 - ACS Publications
It is becoming ever clearer that the presence of carbohydrate units in naturally occurring
structures and their mimetics has a dramatic effect on their physical, chemical, and biological …
structures and their mimetics has a dramatic effect on their physical, chemical, and biological …
Glycosamino acids: building blocks for combinatorial synthesis—implications for drug discovery
F Schweizer - Angewandte chemie international edition, 2002 - Wiley Online Library
The unique functions of carbohydrates, including energy storage, transport, modulation of
protein function, intercellular adhesion, signal transduction, malignant transformation, and …
protein function, intercellular adhesion, signal transduction, malignant transformation, and …
Recent advances in synthesis of sugar and nucleoside coumarin conjugates and their biological impact
S Kumar, A Arora, R Kumar, NN Senapati… - Carbohydrate …, 2023 - Elsevier
Naturally occurring coumarin and sugar molecules have a diverse range of applications
along with superior biocompatibility. Coumarin, a member of the benzopyrone family …
along with superior biocompatibility. Coumarin, a member of the benzopyrone family …
Dynamic combinatorial carbohydrate libraries: probing the binding site of the concanavalin A lectin
O Ramström, S Lohmann… - … A European Journal, 2004 - Wiley Online Library
Dynamic combinatorial chemistry (DCC) has emerged as an efficient approach to
receptor/ligand identification based on the generation of combinatorial libraries by reversible …
receptor/ligand identification based on the generation of combinatorial libraries by reversible …
Glycosyldisulfides from dynamic combinatorial libraries as O-glycoside mimetics for plant and endogenous lectins: their reactivities in solid-phase and cell assays and …
S André, Z Pei, HC Siebert, O Ramström… - Bioorganic & medicinal …, 2006 - Elsevier
Dynamic combinatorial library design exploiting the thiol–disulfide exchange readily affords
access to glycosyldisulfides. In order to reveal lectin-binding properties of this type of non …
access to glycosyldisulfides. In order to reveal lectin-binding properties of this type of non …
Chemical biology of dynamic combinatorial libraries
O Ramström, T Bunyapaiboonsri, S Lohmann… - … et Biophysica Acta (BBA …, 2002 - Elsevier
Dynamic combinatorial chemistry (DCC) is a recently introduced supramolecular approach
to generate libraries of chemical compounds based on reversible exchange processes. The …
to generate libraries of chemical compounds based on reversible exchange processes. The …
Advances in the use of synthetic combinatorial chemistry: mixture-based libraries
The conceptual and technical approaches that led to the explosive growth of combinatorial
chemistry began approximately 20 years ago. In the past decade, combinatorial chemistry …
chemistry began approximately 20 years ago. In the past decade, combinatorial chemistry …
Synthesis of di-branched heptasaccharide by one-pot glycosylation using seven independent building blocks
H Tanaka, M Adachi, H Tsukamoto, T Ikeda… - Organic …, 2002 - ACS Publications
We describe an efficient synthesis of di-branched heptasaccharide 1 having phytoalexin
elicitor activity in soybeans by one-pot glycosylation. The synthesis involves chemo-and …
elicitor activity in soybeans by one-pot glycosylation. The synthesis involves chemo-and …
Combinatorial synthesis of natural products
J Nielsen - Current opinion in chemical biology, 2002 - Elsevier
Combinatorial syntheses allow production of compound libraries in an expeditious and
organized manner immediately applicable for high-throughput screening. Natural products …
organized manner immediately applicable for high-throughput screening. Natural products …