3D printed medicines: A new branch of digital healthcare
Abstract Three-dimensional printing (3DP) is a highly disruptive technology with the
potential to change the way pharmaceuticals are designed, prescribed and produced …
potential to change the way pharmaceuticals are designed, prescribed and produced …
[HTML][HTML] An update on oral drug delivery via intestinal lymphatic transport
Orally administered drug entities have to survive the harsh gastrointestinal environment,
penetrate the enteric epithelia and circumvent hepatic metabolism before reaching the …
penetrate the enteric epithelia and circumvent hepatic metabolism before reaching the …
Fused deposition modeling (FDM) 3D printed tablets for intragastric floating delivery of domperidone
X Chai, H Chai, X Wang, J Yang, J Li, Y Zhao, W Cai… - Scientific reports, 2017 - nature.com
The aim of this study was to explore the feasibility of fused deposition modeling (FDM) 3D
printing to prepare intragastric floating sustained release (FSR) tablets. Domperidone …
printing to prepare intragastric floating sustained release (FSR) tablets. Domperidone …
[HTML][HTML] The influence of the gut microbiota on the bioavailability of oral drugs
X Zhang, Y Han, W Huang, M Jin, Z Gao - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Due to its safety, convenience, low cost and good compliance, oral administration attracts
lots of attention. However, the efficacy of many oral drugs is limited to their unsatisfactory …
lots of attention. However, the efficacy of many oral drugs is limited to their unsatisfactory …
[HTML][HTML] Invited review: Characterization of new probiotics from dairy and nondairy products—Insights into acid tolerance, bile metabolism and tolerance, and …
The selection of potential probiotic strains that possess the physiological capacity of
performing successfully in the gastrointestinal tract (GIT) is a critical challenge. Probiotic …
performing successfully in the gastrointestinal tract (GIT) is a critical challenge. Probiotic …
Recent advances in colon drug delivery systems
R Arévalo-Pérez, C Maderuelo, JM Lanao - Journal of controlled release, 2020 - Elsevier
As a result of its ability to target certain drugs and/or peptides to the colonic region for the
treatment of several diseases while avoiding systemic absorption and potential side effects …
treatment of several diseases while avoiding systemic absorption and potential side effects …
Curcumin-loaded core-shell biopolymer nanoparticles produced by the pH-driven method: Physicochemical and release properties
In this study, core-shell biopolymer nanoparticles were fabricated for the encapsulation and
delivery of curcumin using a pH-driven method. The influences of the coating composition …
delivery of curcumin using a pH-driven method. The influences of the coating composition …
The therapeutic importance of acid-base balance
BN Quade, MD Parker, R Occhipinti - Biochemical Pharmacology, 2021 - Elsevier
Baking soda and vinegar have been used as home remedies for generations and today we
are only a mouse-click away from claims that baking soda, lemon juice, and apple cider …
are only a mouse-click away from claims that baking soda, lemon juice, and apple cider …
Predicting oral drug absorption: mini review on physiologically-based pharmacokinetic models
L Lin, H Wong - Pharmaceutics, 2017 - mdpi.com
Most marketed drugs are administered orally, despite the complex process of oral
absorption that is difficult to predict. Oral bioavailability is dependent on the interplay …
absorption that is difficult to predict. Oral bioavailability is dependent on the interplay …
Food effects on oral drug absorption: application of physiologically-based pharmacokinetic modeling as a predictive tool
L Cheng, H Wong - Pharmaceutics, 2020 - mdpi.com
The bioavailability of an orally administered small molecule is often dictated by drug-specific
physicochemical characteristics and is influenced by many biological processes. For …
physicochemical characteristics and is influenced by many biological processes. For …