3D printed medicines: A new branch of digital healthcare

A Awad, SJ Trenfield, S Gaisford, AW Basit - International journal of …, 2018 - Elsevier
Abstract Three-dimensional printing (3DP) is a highly disruptive technology with the
potential to change the way pharmaceuticals are designed, prescribed and produced …

[HTML][HTML] An update on oral drug delivery via intestinal lymphatic transport

Z Zhang, Y Lu, J Qi, W Wu - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Orally administered drug entities have to survive the harsh gastrointestinal environment,
penetrate the enteric epithelia and circumvent hepatic metabolism before reaching the …

Fused deposition modeling (FDM) 3D printed tablets for intragastric floating delivery of domperidone

X Chai, H Chai, X Wang, J Yang, J Li, Y Zhao, W Cai… - Scientific reports, 2017 - nature.com
The aim of this study was to explore the feasibility of fused deposition modeling (FDM) 3D
printing to prepare intragastric floating sustained release (FSR) tablets. Domperidone …

[HTML][HTML] The influence of the gut microbiota on the bioavailability of oral drugs

X Zhang, Y Han, W Huang, M Jin, Z Gao - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Due to its safety, convenience, low cost and good compliance, oral administration attracts
lots of attention. However, the efficacy of many oral drugs is limited to their unsatisfactory …

[HTML][HTML] Invited review: Characterization of new probiotics from dairy and nondairy products—Insights into acid tolerance, bile metabolism and tolerance, and …

MM Ayyash, AK Abdalla, NS AlKalbani, MA Baig… - Journal of Dairy …, 2021 - Elsevier
The selection of potential probiotic strains that possess the physiological capacity of
performing successfully in the gastrointestinal tract (GIT) is a critical challenge. Probiotic …

Recent advances in colon drug delivery systems

R Arévalo-Pérez, C Maderuelo, JM Lanao - Journal of controlled release, 2020 - Elsevier
As a result of its ability to target certain drugs and/or peptides to the colonic region for the
treatment of several diseases while avoiding systemic absorption and potential side effects …

Curcumin-loaded core-shell biopolymer nanoparticles produced by the pH-driven method: Physicochemical and release properties

Z Li, Q Lin, DJ McClements, Y Fu, H Xie, T Li, G Chen - Food Chemistry, 2021 - Elsevier
In this study, core-shell biopolymer nanoparticles were fabricated for the encapsulation and
delivery of curcumin using a pH-driven method. The influences of the coating composition …

The therapeutic importance of acid-base balance

BN Quade, MD Parker, R Occhipinti - Biochemical Pharmacology, 2021 - Elsevier
Baking soda and vinegar have been used as home remedies for generations and today we
are only a mouse-click away from claims that baking soda, lemon juice, and apple cider …

Predicting oral drug absorption: mini review on physiologically-based pharmacokinetic models

L Lin, H Wong - Pharmaceutics, 2017 - mdpi.com
Most marketed drugs are administered orally, despite the complex process of oral
absorption that is difficult to predict. Oral bioavailability is dependent on the interplay …

Food effects on oral drug absorption: application of physiologically-based pharmacokinetic modeling as a predictive tool

L Cheng, H Wong - Pharmaceutics, 2020 - mdpi.com
The bioavailability of an orally administered small molecule is often dictated by drug-specific
physicochemical characteristics and is influenced by many biological processes. For …