Exosomes: from garbage bins to promising therapeutic targets

M H. Rashed, E Bayraktar, G K. Helal… - International journal of …, 2017 - mdpi.com
Intercellular communication via cell-released vesicles is a very important process for both
normal and tumor cells. Cell communication may involve exosomes, small vesicles of …

The role of myeloid-derived suppressor cells (MDSC) in cancer progression

V Umansky, C Blattner, C Gebhardt, J Utikal - Vaccines, 2016 - mdpi.com
The immunosuppressive tumor microenvironment represents not only one of the key factors
stimulating tumor progression but also a strong obstacle for efficient tumor immunotherapy …

Extracellular membrane vesicles as a mechanism of cell-to-cell communication: advantages and disadvantages

G Turturici, R Tinnirello, G Sconzo… - American Journal of …, 2014 - journals.physiology.org
Microvesicles represent a newly identified mechanism of intercellular communication. Two
different types of microvesicles have been identified: membrane-derived vesicles (EVs) and …

[HTML][HTML] Exosomes/microvesicles as a mechanism of cell-to-cell communication

G Camussi, MC Deregibus, S Bruno, V Cantaluppi… - Kidney international, 2010 - Elsevier
Microvesicles (MVs) are circular fragments of membrane released from the endosomal
compartment as exosomes or shed from the surface membranes of most cell types. An …

From the cradle to the grave: the role of macrophages in erythropoiesis and erythrophagocytosis

TRL Klei, SM Meinderts, TK van den Berg… - Frontiers in …, 2017 - frontiersin.org
Erythropoiesis is a highly regulated process where sequential events ensure the proper
differentiation of hematopoietic stem cells into, ultimately, red blood cells (RBCs) …

Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery

J Ratajczak, K Miekus, M Kucia, J Zhang, R Reca… - Leukemia, 2006 - nature.com
Membrane-derived vesicles (MV) are released from the surface of activated eucaryotic cells
and exert pleiotropic effects on surrounding cells. Since the maintenance of pluripotency …

Membrane-derived microvesicles: important and underappreciated mediators of cell-to-cell communication

J Ratajczak, M Wysoczynski, F Hayek… - Leukemia, 2006 - nature.com
Normal and malignant cells shed from their surface membranes as well as secrete from the
endosomal membrane compartment circular membrane fragments called microvesicles …

Extracellular vesicles secreted by atherogenic macrophages transfer microRNA to inhibit cell migration

MA Nguyen, D Karunakaran, M Geoffrion… - … , and vascular biology, 2018 - Am Heart Assoc
Objective—During inflammation, macrophages secrete vesicles carrying RNA, protein, and
lipids as a form of extracellular communication. In the vessel wall, extracellular vesicles …

Growth factors, CD34 positive cells, and fibrin network analysis in concentrated growth factors fraction

LF Rodella, G Favero, R Boninsegna… - Microscopy research …, 2011 - Wiley Online Library
An interesting clinical option for optimizing healing tissue is the use of platelet concentrate.
Platelets contain high quantities of growth factors, among these TGF‐β1 and VEGF, which …

CXCR4–SDF-1 signalling, locomotion, chemotaxis and adhesion

M Kucia, K Jankowski, R Reca, M Wysoczynski… - Journal of molecular …, 2004 - Springer
Chemokines, small pro-inflammatory chemoattractant cytokines, that bind to specific G-
protein-coupled seven-span transmembrane receptors present on plasma membranes of …