Pathogenicity and virulence of Hepatitis B virus

YC Chuang, KN Tsai, JHJ Ou - Virulence, 2022 - Taylor & Francis
Hepatitis B virus (HBV) is a hepatotropic virus and an important human pathogen. There are
an estimated 296 million people in the world that are chronically infected by this virus, and …

Hepatocellular carcinoma: current trends in worldwide epidemiology, risk factors, diagnosis and therapeutics

MIF Shariff, IJ Cox, AI Gomaa, SA Khan… - Expert review of …, 2009 - Taylor & Francis
Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death
worldwide and, owing to changes in the prevalence of the two major risk factors, hepatitis B …

Gender disparity of hepatocellular carcinoma: the roles of sex hormones

SH Yeh, PJ Chen - Oncology, 2010 - karger.com
Men have a higher incidence of hepatocellular carcinoma (HCC) than women.
Epidemiologic and animal studies have suggested that it might be due to the stimulatory …

Gender differences in the pathogenesis and risk factors of hepatocellular carcinoma

R Nevola, G Tortorella, V Rosato, L Rinaldi, S Imbriani… - Biology, 2023 - mdpi.com
Simple Summary Significant gender disparities have been highlighted in the incidence,
aggressiveness, and prognosis of HCC. A different epidemiological distribution of the risk …

Androgen receptor (AR) differential roles in hormone-related tumors including prostate, bladder, kidney, lung, breast and liver

C Chang, SO Lee, S Yeh, TM Chang - Oncogene, 2014 - nature.com
The androgen receptor (AR) is expressed in many cell types and the androgen/AR signaling
has been found to have important roles in modulating tumorigenesis and metastasis in …

C-terminal truncated HBx initiates hepatocarcinogenesis by downregulating TXNIP and reprogramming glucose metabolism

Y Zhang, Q Yan, L Gong, H Xu, B Liu, X Fang, D Yu… - Oncogene, 2021 - nature.com
Chronic hepatitis B virus (HBV) infection is strongly associated with the initiation and
development of hepatocellular carcinoma (HCC). However, the genetic alterations and …

A comparison of the surgical outcomes among patients with HBV-positive, HCV-positive, and non-B non-C hepatocellular carcinoma: a nationwide study of 11,950 …

T Utsunomiya, M Shimada, M Kudo, T Ichida… - Annals of …, 2015 - journals.lww.com
Objective: To compare the prognostic factors and outcomes after hepatic resection among
patients with hepatitis B virus (HBV)-positive, hepatitis C virus (HCV)-positive, and negative …

Gender disparity in chronic hepatitis B: mechanisms of sex hormones

SH Wang, PJ Chen, SH Yeh - Journal of gastroenterology and …, 2015 - Wiley Online Library
Hepatitis B virus (HBV) is a common human pathogen transmitted worldwide, and its chronic
infection is a well‐known risk factor for hepatocellular carcinoma (HCC). The sex disparity of …

Gender disparity in hepatocellular carcinoma (HCC): multiple underlying mechanisms

B Zheng, YJ Zhu, HY Wang, L Chen - Science China Life Sciences, 2017 - Springer
On the global scale, hepatitis B virus (HBV) infection is the main cause of hepatocellular
carcinoma (HCC) especially in regions of Asia where HBV infection is endemic …

Hepatitis B virus X protein: molecular functions and its role in virus life cycle and pathogenesis

S Benhenda, D Cougot, MA Buendia… - Advances in cancer …, 2009 - Elsevier
Despite the existence of effective vaccines, HBV infection remains a major health problem
with 2 billion people infected worldwide. Among them, 350 million are chronically infected, a …