Herpetic infections have plagued humanity for thousands of years, but only recently have
advances in antiviral medications and supportive treatments equipped physicians to combat …

Virus infections usually begin in peripheral tissues and can invade the mammalian nervous
system (NS), spreading into the peripheral (PNS) and more rarely the central (CNS) nervous …

The olfactory nerve consists mainly of olfactory receptor neurons and directly connects the
nasal cavity with the central nervous system (CNS). Each olfactory receptor neuron projects …

Alphaherpesviruses like herpes simplex virus are large DNA viruses characterized by their
ability to establish lifelong latent infection in neurons. As for all herpesviruses …

Recent work has demonstrated that following the clearance of infection a stable population
of memory T cells remains present in peripheral organs and contributes to the control of …

The order Herpesvirales contains viruses infecting animals from molluscs to men with a
common virion morphology which have been classified into the families Herpesviridae …

A growing body of epidemiologic and experimental data point to chronic bacterial and viral
infections as possible risk factors for neurodegenerative diseases, including Alzheimer's …

Neurological disorders–disorders of the brain, spine and associated nerves–are a leading
contributor to global disease burden with a shockingly large associated economic cost …

Viral infections are a major cause of human disease. Although most viruses replicate in
peripheral tissues, some have developed unique strategies to move into the nervous …

It is now clear that transport on microtubules by dynein and kinesin family motors has an
important if not critical role in the replication and spread of many different viruses …