[HTML][HTML] Pharmaceutical approaches on antimicrobial resistance: prospects and challenges

F Nainu, AD Permana, NJN Djide, QK Anjani… - Antibiotics, 2021 - mdpi.com
The rapid increase in pathogenic microorganisms with antimicrobial resistant profiles has
become a significant public health problem globally. The management of this issue using …

[HTML][HTML] Research updates of plasmid-mediated aminoglycoside resistance 16S rRNA methyltransferase

W Yang, F Hu - Antibiotics, 2022 - mdpi.com
With the wide spread of multidrug-resistant bacteria, a variety of aminoglycosides have been
used in clinical practice as one of the effective options for antimicrobial combinations …

The effect of operating strategies on the anaerobic digestion of gentamicin mycelial residues: Insights into the enhancement of methane production and attenuation of …

M Jiang, P Wang, H Liu, X Dai, S Song… - … Science & Technology, 2022 - ACS Publications
Anaerobic digestion (AD) has been widely employed for converting various biowastes into
renewable energy. However, AD of gentamicin mycelial residues (GMRs, a byproduct of …

Antimicrobial treatment options for difficult-to-treat resistant gram-negative bacteria causing cystitis, pyelonephritis, and prostatitis: a narrative review

A Chou, E Welch, A Hunter, BW Trautner - Drugs, 2022 - Springer
Urinary tract infections, including cystitis, acute pyelonephritis, and prostatitis, are among the
most common diagnoses prompting antibiotic prescribing. The rise in antimicrobial …

Comparison of in vitro activities of plazomicin and other aminoglycosides against clinical isolates of Klebsiella pneumoniae and Escherichia coli

G İnce, HC Mirza, A Üsküdar Güçlü… - Journal of …, 2021 - academic.oup.com
Objectives To compare the in vitro activity of plazomicin and two older aminoglycosides
(gentamicin and amikacin) against 180 isolates of Escherichia coli and Klebsiella …

# AMRrounds: a systematic educational approach for navigating bench to bedside antimicrobial resistance

E Liu, AM Prinzi, J Borjan, SL Aitken… - JAC-Antimicrobial …, 2023 - academic.oup.com
Antimicrobial resistance (AMR) continues to serve as a major global health crisis. Clinicians
practising in this modern era are faced with ongoing challenges in the therapeutic …

Multicenter Clinical Evaluation of ETEST Plazomicin (PLZ) for Susceptibility Testing of Enterobacterales

LS Blanchard, A Van Belkum… - Journal of Clinical …, 2022 - Am Soc Microbiol
Plazomicin (PLZ), brand name ZEMDRI (Cipla Therapeutics), is a novel aminoglycoside
antibiotic approved by the US Food and Drug Administration (FDA) for treatment of …

Design, Synthesis and Activity Evaluation Against Drug‐Resistant Bacteria of 6'‐Amidine Modified Aminoglycoside Derivatives

J Xu, X Zhang, G Xu, Y Zhang, H Li, J Shi - ChemistrySelect, 2024 - Wiley Online Library
The issue of bacterial resistance has become a matter of significant concern globally,
prompting extensive research into the development and clinical application of …

[HTML][HTML] Can isepamicin be a potential option for extended spectrum beta-lactamases and carbapenemases expressing Escherichia coli?

YD Bakthavatchalam, F Abdullah, D Srinivasan… - … and Global Health, 2024 - Elsevier
Abstract Background Beta-lactamase expressing Enterobacterales are challenging to treat.
The potency of aminoglycosides as a bactericidal agent has increased interest in using them …

[PDF][PDF] Trends of Antibiotic Resistance in Multidrug-Resistant Pathogens Isolated from Blood Cultures in a Four-Year Period.

L Oksuz, G Altay, Z Aktas - Clinical Laboratory, 2023 - researchgate.net
Background: Multidrug-resistant organisms cause serious infections with significant
morbidity and mortality in the worldwide. These organisms have been identified as urgent …