[HTML][HTML] Investigation of antioxidant and antibacterial effects of citrus fruits peels extracts using different extracting agents: Phytochemical analysis with in silico studies

M Saleem, AI Durani, A Asari, M Ahmed, M Ahmad… - Heliyon, 2023 - cell.com
The peels extracted from various citrus species are major source of phenols, flavonoids and
anti-microbial agents. The purpose of this study was a detailed investigation of the …

[HTML][HTML] In vitro and in silico approaches for the evaluation of antimicrobial activity, time-kill kinetics, and anti-biofilm potential of thymoquinone (2-Methyl-5-propan-2 …

KA Qureshi, M Imtiaz, A Parvez, PK Rai, M Jaremko… - Antibiotics, 2022 - mdpi.com
Thymoquinone (2-methyl-5-propan-2-ylcyclohexa-2, 5-diene-1, 4-dione; TQ), a principal
bioactive phytoconstituent of Nigella sativa essential oil, has been reported to have high …

[HTML][HTML] Antiprotozoal Activity of Thymoquinone (2-Isopropyl-5-methyl-1,4-benzoquinone) for the Treatment of Leishmania major-Induced Leishmaniasis: In Silico and …

KA Qureshi, M Imtiaz, I Al Nasr, WS Koko, TA Khan… - Antibiotics, 2022 - mdpi.com
Leishmaniasis, a neglected tropical parasitic disease (NTPD), is caused by various
Leishmania species. It transmits through the bites of the sandfly. The parasite is evolving …

Opportunities and Challenges in the Development of Antiparasitic Drugs

M Bello‐Akinosho, KO Afolabi… - Parasitic Infections …, 2023 - Wiley Online Library
Parasitic infections remain a major public health problem worldwide, affecting millions of
people annually. Since parasitic infections are linked to poverty, marketing their drugs is less …

Comparative study of volatile oil constituents, anti-microbial properties, and antibiofilm activities in Eucalyptus camaldulensis and Eucalyptus globulus: insights from …

HA Mohammed, A Aspatwar, AF Aljarbooa… - Journal of Essential …, 2024 - Taylor & Francis
Eucalyptus is a fragrant plant with a highly volatile oil content grown worldwide. This study
investigated the phytochemical and biological features of two Eucalyptus species, E …

[HTML][HTML] Antifungal activity of compounds from Gordonia sp. WA8-44 isolated from the gut of Periplaneta americana and molecular docking studies

W Liu, E Li, L Liu, F Tian, X Luo, Y Cai, J Wang, X Jin - Heliyon, 2023 - cell.com
Invasive fungal infections are on the rise, leading to a continuous demand for antifungal
antibiotics. Rare actinomycetes have been shown to contain a variety of interesting …

Acetylsalicylic acid-sulfa drugs conjugates as potential urease inhibitors and anti-inflammatory agents: bio-oriented drug synthesis, molecular docking, and dynamics …

S Ahmad, M Abdul Qadir, M Ahmed… - Journal of …, 2023 - Taylor & Francis
To explore the new mode of action and reduce side effects, making conjugates of existing
drugs is becoming an attractive tool in the realm of medicinal chemistry. In this work, we …

Structural and functional analyses of SARS COV-2 RNA-dependent RNA polymerase protein and complementary vs. Synthetic drugs against COVID-19 and the …

A Unar, M Imtiaz, TT Trung, M Rafiq… - Current …, 2022 - ingentaconnect.com
Background: RNA-dependent RNA polymerase (RdRp) contributes to the transcription cycle
of the SARS-CoV-2 virus with the possible assistance of nsp-7-8 cofactors. Objective: The …

Streptomyces isolated from bird feathers as a potential source for novel antibiotics

A Sarmiento-Vizcaíno, LA García, G Blanco - Archives of Microbiology, 2023 - Springer
Streptomyces, the main source of antibiotics essential for human health, are widely
distributed in nature among terrestrial, oceanic and atmospheric environments. New trends …

Cutaneous Leishmaniasis: Physiopathology, Molecular Diagnostic, and Therapeutic Approaches

A Balahbib, A Hmamouch, A El Allam… - Progress In Microbes …, 2023 - hh-publisher.com
This in-depth study explores various aspects of cutaneous leishmaniasis, shedding light on
the physiopathology of the infection, advances in molecular diagnostic techniques, and …