Alzheimer's disease and related dementias (ADRD) are among the top contributors to
disability and mortality in later life. As with many chronic conditions, aging is the single most …

Human T cells have a diverse T‐cell receptor (TCR) repertoire that endows them with the
ability to identify and defend against a broad spectrum of antigens. The universe of possible …

Studies over the last 100 years have suggested a link between inflammation, infectious
disease, and Alzheimer's Disease (AD). Understanding how the immune system changes …

Neurological conditions such as Alzheimer's disease (AD) and related dementias (ADRD)
present with many challenges due to the heterogeneity of the related disease (s), making it …

Pediatric and adult autoimmune encephalitis (AE) are often associated with Abs to the NR1
subunit of the N-methyl-d-aspartate (NMDA) receptor (NMDAR). Very little is known …

The neurovascular unit, composed of vascular endothelium, vascular smooth muscle,
extracellular matrix components, pericytes, astrocytes, microglia, and neurons, allows the …

Inflammatory biomarkers in plasma are associated with dementia. Thus, we examined the
association of 18 types of peripheral immune cells, measured as proportions of their immune …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with
memory decline and cognitive impairment, which is related to hallmark protein aggregates …

ABSTRACT Background Processes that drive Alzheimer's disease pathogenesis have long
been considered to occur within the central nervous system, yet recent studies have …

Adaptive immune receptor (IR) chemical features have been used as signatures of an
immune response for numerous medical conditions, raising the question of whether certain …