The cell imposes multiple barriers to virus entry. However, viruses exploit fundamental
cellular processes to gain entry to cells and deliver their genetic cargo. Virus entry pathways …

We review the molecular and epidemiological characteristics of cetacean morbillivirus
(CeMV) and the diagnosis and pathogenesis of associated disease, with six different strains …

Triple-negative breast cancer (TNBC) remains the most lethal form of breast cancer, and
effective targeted therapeutics are in urgent need to improve the poor prognosis of TNBC …

Measles virus is an aerosol-transmitted virus that affects more than 10 million children each
year and accounts for approximately 120,000 deaths,. Although it was long believed to …

Measles virus is a highly contagious negative strand RNA virus that is transmitted via the
respiratory route and causes systemic disease in previously unexposed humans and non …

Peste des petits ruminants (PPR) is caused by a Morbillivirus that belongs to the family
Paramyxoviridae. PPR is an acute, highly contagious and fatal disease primarily affecting …

Early-stage clinical trials of oncolytic virotherapy have reported the safety of several virus
platforms, and viruses from three families have progressed to advanced efficacy trials. In …

Morbilliviruses are among the most contagious viral pathogens of mammals. Although
previous metagenomic surveys have identified morbillivirus sequences in bats, full-length …

Emerging virus diseases are a major threat to human and veterinary public health. With new
examples occurring approximately one each year, the majority are viruses originating from …

Bicycle toxin conjugates (BTCs) are a promising new class of molecules for targeted delivery
of toxin payloads into tumors. Herein we describe the discovery of BT8009, a Nectin-4 …