From maternal diet to neurodevelopmental disorders: a story of neuroinflammation

M Bordeleau, L Fernandez de Cossio… - Frontiers in Cellular …, 2021 - frontiersin.org
Providing the appropriate quantity and quality of food needed for both the mother's well-
being and the healthy development of the offspring is crucial during pregnancy. However …

The special relationship: glia–neuron interactions in the neuroendocrine hypothalamus

J Clasadonte, V Prevot - Nature Reviews Endocrinology, 2018 - nature.com
Natural fluctuations in physiological conditions require adaptive responses involving rapid
and reversible structural and functional changes in the hypothalamic neuroendocrine …

[HTML][HTML] The timing of the excitatory-to-inhibitory GABA switch is regulated by the oxytocin receptor via KCC2

M Leonzino, M Busnelli, F Antonucci, C Verderio… - Cell reports, 2016 - cell.com
Oxytocin and its receptor (Oxtr) play a crucial role in the postnatal transition of neuronal
GABA neurotransmission from excitatory to inhibitory, a developmental process known as …

Cross talk between AT1 receptors and Toll-like receptor 4 in microglia contributes to angiotensin II-derived ROS production in the hypothalamic paraventricular …

VC Biancardi, AM Stranahan… - American Journal …, 2016 - journals.physiology.org
ANG II is thought to increase sympathetic outflow by increasing oxidative stress and
promoting local inflammation in the paraventricular nucleus (PVN) of the hypothalamus …

[HTML][HTML] [Na+] increases in body fluids sensed by central Nax induce sympathetically mediated blood pressure elevations via H+-dependent activation of ASIC1a

K Nomura, TY Hiyama, H Sakuta, T Matsuda, CH Lin… - Neuron, 2019 - cell.com
Increases in sodium concentrations ([Na+]) in body fluids elevate blood pressure (BP) by
enhancing sympathetic nerve activity (SNA). However, the mechanisms by which …

AT1 receptors: their actions from hypertension to cognitive impairment

H Wu, Q Sun, S Yuan, J Wang, F Li, H Gao… - Cardiovascular …, 2022 - Springer
Hypertension is one of the most prevalent cardiovascular disorders worldwide, affecting 1.13
billion people, or 14% of the global population. Hypertension is the single biggest risk factor …

Salt, water and nephron: Mechanisms of action and link to hypertension and chronic kidney disease

Q Qian - Nephrology, 2018 - Wiley Online Library
Our knowledge on sodium and water homeostasis and regulation continues to evolve. A
considerable amount of new information in this area has emerged in recent years. This …

Genetic forms of nephrogenic diabetes insipidus (NDI): Vasopressin receptor defect (X-linked) and aquaporin defect (autosomal recessive and dominant)

DG Bichet, D Bockenhauer - … Practice & Research Clinical Endocrinology & …, 2016 - Elsevier
Nephrogenic diabetes insipidus (NDI), which can be inherited or acquired, is characterized
by an inability to concentrate urine despite normal or elevated plasma concentrations of the …

Mechanism-based strategies to prevent salt sensitivity and salt-induced hypertension

TW Kurtz, M Pravenec, SE DiCarlo - Clinical Science, 2022 - portlandpress.com
High-salt diets are a major cause of hypertension and cardiovascular (CV) disease. Many
governments are interested in using food salt reduction programs to reduce the risk for salt …

Vasopressin & oxytocin in control of the cardiovascular system: an updated review

N Japundžić-Žigon, M Lozić… - Current …, 2020 - ingentaconnect.com
Since the discovery of vasopressin (VP) and oxytocin (OT) in 1953, considerable knowledge
has been gathered about their roles in cardiovascular homeostasis. Unraveling VP …