Radiotherapy (RT) is delivered for purposes of local control, but can also exert systemic
effect on remote and non-irradiated tumor deposits, which is called abscopal effect. The view …

Neutrophils are the frontline cells in response to microbial infections and are involved in a
range of inflammatory disorders in the body. In recent years, neutrophils have gained …

Carcinomas are complex ecosystems composed of cancer, stromal and immune cells.
Communication between these cells and their microenvironments induces cancer …

Chemodynamic therapy (CDT) catalyzed by transition metal and starvation therapy
catalyzed by intracellular metabolite oxidases are both classic tumor treatments based on …

Cancer, one of the most dangerous diseases with a high mortality rate, has attracted much
attention and interest. Advances in tissue engineering and microfluidics have led to the …

A new anticancer strategy to exploit abnormal metabolism of cancer cells rather than to
merely control the drug release or rearrange the tumor microenvironment is reported. An …

Solid tumors have a unique tumor microenvironment (TME), which includes hypoxia, low
acidity, and high hydrogen peroxide and glutathione (GSH) levels, among others. These …

The newly emerging nanotheranostic strategies including photodynamic therapy (PDT),
photothermal therapy (PTT) and sonodynamic therapy (SDT) have exhibited their …

Background Chemodynamic therapy is a promising cancer treatment with specific
therapeutic effect at tumor sites, as toxic hydroxyl radical (· OH) could only be generated by …

Background The tumour–stroma ratio (TSR) is identified as a promising prognostic
parameter for breast cancer, but the cutoff TSR value is mostly assessed by visual …