[HTML][HTML] Role of fibrinolytic enzymes in anti-thrombosis therapy

F Altaf, S Wu, V Kasim - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Thrombosis, a major cause of deaths in this modern era responsible for 31% of all global
deaths reported by WHO in 2017, is due to the aggregation of fibrin in blood vessels which …

[HTML][HTML] Marine microbial fibrinolytic enzymes: an overview of source, production, biochemical properties and thrombolytic activity

N Barzkar, ST Jahromi, F Vianello - Marine Drugs, 2022 - mdpi.com
Cardiovascular diseases (CVDs) have emerged as a major threat to global health resulting
in a decrease in life expectancy with respect to humans. Thrombosis is one of the foremost …

Purification, physicochemical properties, and statistical optimization of fibrinolytic enzymes especially from fermented foods: a comprehensive review

AMM Ali, SCB Bavisetty - International Journal of Biological …, 2020 - Elsevier
Fibrinolytic enzymes are proteases responsible for cleavage of fibrin mesh in thrombus clots,
which are the primary causative agents in cardiovascular diseases. Developing safe …

[HTML][HTML] Thrombolytic enzymes of microbial origin: a review

D Diwan, Z Usmani, M Sharma, JW Nelson… - International journal of …, 2021 - mdpi.com
Enzyme therapies are attracting significant attention as thrombolytic drugs during the current
scenario owing to their great affinity, specificity, catalytic activity, and stability. Among various …

[HTML][HTML] Structural biology and protein engineering of thrombolytics

J Mican, M Toul, D Bednar, J Damborsky - Computational and structural …, 2019 - Elsevier
Myocardial infarction and ischemic stroke are the most frequent causes of death or disability
worldwide. Due to their ability to dissolve blood clots, the thrombolytics are frequently used …

Hydrogel-based Chlorella vulgaris extracts: a new topical formulation for wound healing treatment

RG de Melo, AF de Andrade, RP Bezerra… - Journal of Applied …, 2019 - Springer
Chlorella vulgaris is a microalga which contains a variety of bioactive compounds. Chlorella
has been used in different fields for several years and proved attractive to the …

Identification, characterization, and engineering of glycosylation in thrombolytics

M Toul, V Slonkova, J Mican, A Urminsky… - Biotechnology …, 2023 - Elsevier
Cardiovascular diseases, such as myocardial infarction, ischemic stroke, and pulmonary
embolism, are the most common causes of disability and death worldwide. Blood clot …

Research progress on the fibrinolytic enzymes produced from traditional fermented foods

P Wang, C Peng, X Xie, X Deng… - Food Science & …, 2023 - Wiley Online Library
Cardiovascular diseases (CVDs) are a global health problem and leading cause of death
worldwide. Thrombus formation, one of the CVDs, is essentially the formation of fibrin clots …

Fibrinolytic enzyme from Arthrospira platensis cultivated in medium culture supplemented with corn steep liquor

PDS de Barros, PEC e Silva, TP Nascimento… - International Journal of …, 2020 - Elsevier
Artrhospira (Spirulina) platensis produced fibrinolytic enzyme under mixotrophic conditions
using corn steep liquor (CSL). The enzyme was extracted, purified by combination of two …

[HTML][HTML] Diverse origins of fibrinolytic enzymes: A comprehensive review

C Hazare, P Bhagwat, S Singh, S Pillai - Heliyon, 2024 - cell.com
Fibrinolytic enzymes cleave fibrin which plays a crucial role in thrombus formation which
otherwise leads to cardiovascular diseases. While different fibrinolytic enzymes have been …