Obesity pathogenesis: an endocrine society scientific statement

MW Schwartz, RJ Seeley, LM Zeltser… - Endocrine …, 2017 - academic.oup.com
Obesity is among the most common and costly chronic disorders worldwide. Estimates
suggest that in the United States obesity affects one-third of adults, accounts for up to one …

FTO Common Obesity SNPs Interact with Actionable Environmental Factors: Physical Activity, Sugar-Sweetened Beverages and Wine Consumption

D Chermon, R Birk - Nutrients, 2022 - mdpi.com
Genetic background is estimated to play> 50% in common obesity etiology. FTO single
nucleotide polymorphisms (SNPs) are strongly associated with BMI, typically in European …

Physical activity might reduce the adverse impacts of the FTO gene variant rs3751812 on the body mass index of adults in Taiwan

YC Liaw, YP Liaw, TH Lan - Genes, 2019 - mdpi.com
The fat mass and obesity-associated (FTO) gene is a significant genetic contributor to
polygenic obesity. We investigated whether physical activity (PA) modulates the effect of …

The interaction between FTO rs9939609 and physical activity is associated with a 2‐fold reduction in the risk of obesity in Korean population

HW Cho, HS Jin, YB Eom - American Journal of Human …, 2021 - Wiley Online Library
Objective FTO (fat mass and obesity‐associated) gene is a well‐known genetic risk factor for
obesity. We investigated whether physical activity modulates the effect of FTO rs9939609 on …

FTO rs9939609: T>A Variant and Physical Inactivity as Important Risk Factors for Class III Obesity: A Cross-Sectional Study

E Martínez-López, M Perez-Robles, J Torres-Vanegas… - Healthcare, 2024 - mdpi.com
Background: The prevalence of obesity has been increasing worldwide. It has been reported
that physiological and environmental factors such as diet, culture, physical activity, and …

Effect of FTO and IGF2BP2 gene polymorphisms on duration of pregnancy and Apgar scores in women with gestational diabetes

M Tarnowski, J Bujak, P Kopytko… - Journal of Obstetrics …, 2019 - Taylor & Francis
Gestational diabetes mellitus (GDM) is a metabolic disorder occurring in pregnant women.
The main risk factors include advanced age and obesity. FTO and IGF2BP2 are the genetic …

[HTML][HTML] Relationship between fat mass and obesity-associated (FTO) gene polymorphisms with obesity and metabolic syndrome in ethnic Mongolians

Q Zhang, Y Li, X Shi, X Yuan - Medical Science Monitor …, 2018 - ncbi.nlm.nih.gov
Background The distribution of fat mass and obesity-associated gene (FTO) genes
rs9939609 and rs1421085 in obese and normal ethnic Mongolians was analyzed to …

Physical activity and the association between the FTO rs9939609 polymorphism and obesity in Portuguese children aged 3 to 11 years

L Manco, S Pinho, D Albuquerque… - American Journal of …, 2019 - Wiley Online Library
Objectives To investigate whether objectively measured physical activity (PA) modulates the
association between the FTO rs9939609 polymorphism and obesity variables in a sample of …

Effect of Obesity‐Linked FTO rs9939609 Variant on Physical Activity and Dietary Patterns in Physically Active Men and Women

NR West, J Dorling, AE Thackray, NC Hanson… - Journal of …, 2018 - Wiley Online Library
Single nucleotide polymorphisms (SNPs) in the fat mass and obesity‐associated (FTO)
locus are associated with obesity, but lifestyle factors may modulate the obesity risk related …

FTO rs9939609 A allele influences anthropometric outcome in response to dietary intervention, but not in response to physical exercise program

GA do Nascimento, MD Teixeira, L Furtado-Alle… - European journal of …, 2019 - Springer
Purpose The fat mass and obesity-associated (FTO) gene is involved in energy
homeostasis. The A allele of the rs9939609 (SNP; T> A) is associated with obesity and …