In this Review we discuss data demonstrating recently recognized aspects of neutrophil
homeostasis in the steady state, granulopoiesis in'emergency'conditions and interactions of …

Immune escape is a hallmark of cancer. The dynamic and heterogeneous tumour
microenvironment (TME) causes insufficient infiltration and poor efficacy of natural killer (NK) …

The concept that chemokines, cytokines and pro-inflammatory mediators act in a co-
ordinated fashion to drive the initiation of the inflammatory reaction is well understood. The …

Periodontitis is an inflammatory disease characterized by the destruction of the
periodontium. In the last decade, a new murine model of periodontitis has been widely used …

It is now widely recognized that neutrophils are highly versatile and sophisticated cells that
display de novo synthetic capacity and may greatly extend their lifespan. In addition …

Exposure to pro-inflammatory cytokines, chemokines, mitochondrial contents, and bacterial
and viral products induces neutrophils to transition from a basal state into a primed one …

The terms microparticles (MPs) and microvesicles (MVs) refer to large extracellular vesicles
(EVs) generated from a broad spectrum of cells upon its activation or death by apoptosis …

Highlights•NK cells generate long-lived antigen-specific memory cells.•NK cells regulate
viral load and cytokine production of innate immune cells.•NK cells indirectly modulate …

The global outbreak of coronavirus-2019 (COVID-19) still claims more lives daily around the
world due to the lack of a definitive treatment and the rapid tendency of virus to mutate …

Similar to other cell types, neutrophilic granulocytes also release extracellular vesicles
(EVs), mainly medium-sized microvesicles/microparticles. According to published data …