From poison to promise: The evolution of tetrodotoxin and its potential as a therapeutic
GM Bucciarelli, M Lechner, A Fontes, LB Kats… - Toxins, 2021 - mdpi.com
Tetrodotoxin (TTX) is a potent neurotoxin that was first identified in pufferfish but has since
been isolated from an array of taxa that host TTX-producing bacteria. However, determining …
been isolated from an array of taxa that host TTX-producing bacteria. However, determining …
Toxic relationships and arms-race coevolution revisited
GM Bucciarelli, F Alsalek, LB Kats… - Annual Review of …, 2022 - annualreviews.org
Toxin evolution in animals is one of the most fascinating and complex subjects of scientific
inquiry today. Gaining an understanding of toxins poses a multifaceted challenge given the …
inquiry today. Gaining an understanding of toxins poses a multifaceted challenge given the …
Of poisons and parasites—the defensive role of tetrodotoxin against infections in newts
Classical research on animal toxicity has focused on the role of toxins in protection against
predators, but recent studies suggest these same compounds can offer a powerful defense …
predators, but recent studies suggest these same compounds can offer a powerful defense …
Individual fluctuations in toxin levels affect breeding site fidelity in a chemically defended amphibian
GM Bucciarelli, DB Green… - Proceedings of the …, 2016 - royalsocietypublishing.org
Behaviours that influence habitat selection strongly determine species movement patterns.
One component of animal behaviour that largely influences movement patterns and habitat …
One component of animal behaviour that largely influences movement patterns and habitat …
Feral frogs, native newts, and chemical cues: identifying threats from and management opportunities for invasive African Clawed Frogs in Washington state
Invasive species threaten biodiversity globally. Amphibians are one of the most threatened
vertebrate taxa and are particularly sensitive to invasive species, including other …
vertebrate taxa and are particularly sensitive to invasive species, including other …
Noxious newts and their natural enemies: Experimental effects of tetrodotoxin exposure on trematode parasites and aquatic macroinvertebrates
The dermal glands of many amphibian species secrete toxins or other noxious substances
as a defense strategy against natural enemies. Newts in particular possess the potent …
as a defense strategy against natural enemies. Newts in particular possess the potent …
Native amphibian toxin reduces invasive crayfish feeding with potential benefits to stream biodiversity
GM Bucciarelli, SJ Smith, JJ Choe, PD Shin… - BMC Ecology and …, 2023 - Springer
Background Biodiversity is generally reduced when non-native species invade an
ecosystem. Invasive crayfish, Procambarus clarkii, populate California freshwater streams …
ecosystem. Invasive crayfish, Procambarus clarkii, populate California freshwater streams …
An amphibian toxin phenotype is sexually dimorphic and shows seasonal concordant change between sexes
AR Frey, GM Bucciarelli, DD Hu, LB Kats… - Frontiers in Amphibian …, 2023 - frontiersin.org
Sexually dimorphic phenotypes are consequential to animal survival, and this is especially
apparent with defense phenotypes. Amphibians have poison glands, and several lineages …
apparent with defense phenotypes. Amphibians have poison glands, and several lineages …
[HTML][HTML] The effect of newt toxin on an invasive snail
Invasive species are well documented to impact native species where they are introduced.
In the Santa Monica Mountains, a native species of amphibian, the California newt (Taricha …
In the Santa Monica Mountains, a native species of amphibian, the California newt (Taricha …
Are Pacific Chorus Frogs (Pseudacris regilla) Resistant to Tetrodotoxin (TTX)? Characterizing Potential TTX Exposure and Resistance in an Ecological Associate of Pacific …
KO Montana, V Ramírez-Castañeda… - Journal of …, 2023 - meridian.allenpress.com
Animals that frequently encounter toxins often develop mechanisms of toxin resistance over
evolutionary time. Both predators that consume toxic prey and organisms in physical contact …
evolutionary time. Both predators that consume toxic prey and organisms in physical contact …